Tara Sabo-Attwood, Ph.D.

Associate Professortarasabo-attwood

Office: CEHT-Building 471
Phone: (352) 294-5293
Email: sabo@phhp.ufl.edu

CV

Current Research Interests

  • Mechanisms of particle-induced pulmonary injury
  • Targeted destruction of lung colonizing bacterial biofilms
  • Aquatic toxicology
  • Understanding molecular mechanisms controlling cellular reponses to environmental contaminants including nanomaterials, asbestos and endocrine disrupting compounds such as bisphenol-A
  • Toxicity of nanomaterials in mammalian, terrestrial and aquatic model systems
  • Mechanisms of particle-induced pulmonary injury including fibrosis and COPD
  • The role of hormones and endocrine-active contaminants in the lung and their contribution to gender differences in disease severity
  • Impacts of environmental contaminants on fish reproduction accomplished through in vitro mechanistic and field-based studies
  • Examining modulation of pathogen-driven immune responses in the lung by nanomaterials

Education

  • B.S., Cytogenetics, University of Connecticut, 1996
  • Ph.D., Environmental Toxicology, University of Florida, 2003

Selected Publications

  • Khan IA, Aich N, Afrooz AR, Flora JR, Schierz PA, Ferguson PL, Sabo-Attwood T, Saleh NB. (2013). Fractal structures of single-walled carbon nanotubes in biologically relevant conditions: Role of chirality vs. media conditions. Chemosphere. Nov;93(9):1997-2003. PMID 23920360.
  • Khan, Iftheker; Berge, Nicole; Sabo-Attwood, Tara; Ferguson, Lee; Saleh, Navid. (2013). Single-walled carbon nanotube transport in representative municipal solid waste landfill conditions. Environ Sci Technol. 2013 Aug 6;47(15):8425-33.
  • Khan IA, Afrooz AR, Flora JR, Schierz PA, Ferguson PL, Sabo-Attwood T, Saleh NB. (2013). Chirality affects aggregation kinetics of single-walled carbon nanotubes. Environ Sci Technol. Feb 19;47(4):1844-52. PMID:23343128. • Richey, J., Karmaus, W., Zhang, H., Sabo-Attwood, T., and Steck, S. (2012). The Association of Age, Race and Ethnicity, and Body Mass Index with Sex Steroid Hormone Marker Profiles among Men in the National Health and Nutrition Examination Survey (NHANES III) BMJ Open. Oct 6;2(5).
  • Dominguez GA, Quattro JM, Denslow ND, Kroll KJ, Prucha MS, Porak WF, Grier HJ, Sabo-Attwood TL. (2012). Identification and Temporal Expression of the Vitellogenin Receptor in Largemouth Bass. Biol Reprod. Sep 21;87(3):67.
  • Kashiwada, S., Ariza, M.E., Kawaguchi, T., Nakagame, Y., Jayasinghe, S.B., Gärtner, K., Nakamura, H., Kagami, Y., Sabo-Attwood, T., Ferguson, P.L. and Chandler, G.T. (2012). Silver nano-colloids disrupt medaka embryogenesis through vital gene expressions. Environ Sci Technol. 2012 Jun 5;46(11):6278-87.
  • McLarty, J.L., Melendez, G.C., Levick, S.P., Bennett, S., Sabo-Atwood, T., Brower, G.L. and Janicki, J.S. (2012). Estrogen modulates of inflammation-related genes in male rats following chronic volume overload. Physiol Genomics. Mar 19;44(6):362-73.
  • Handy, R.D., Cornelis, G., Fernandes, T., Tsyusko, O., Decho, A., Metcalfe, C., Sabo-Attwood, T. and Stevens, J (2012). Ecotoxicity test methods for engineered nanomaterials: Practical experiences and recommendations from the bench. Environ Toxicol Chem. Jan;31(1):15-31.
  • Gaertner, K., Quattro, J., Ferguson, P.L., Chandler, G.T. and Sabo-Attwood, T. (2012) Identification and expression of the ecdysone receptor in the harpacticoid copepod, Amphiascus tenuiremis, in response to fipronil. Ecotoxicol Environ Saf. Feb;76(2):39-45.
  • Tara Sabo-Attwood, Jason Unrine, John Stone, Cathy J. Murphy, Sumitra Goshroy, Doug Blom, Paul Bertsch and Lee Newman (2011). Plant Uptake, Distribution and Toxicity of gold nanoparticles. Nanotoxicology, May 16.
  • T Sabo-Attwood, M Ramos-Nino, Maria Eugenia-Ariza, Maximillian MacPherson, Chad Steele, Kelly Butnor and Brooke T. Mossman (2011). Increased lung epithelial cell expression of osteopontin and altered gene expression, cytokine production and inflammation in an inhalation model of pulmonary injury using osteopontin null mice. Amer. J. Pathology, May;178(5):1975-85.
  • Sabo-Attwood, T., Ramos, M.E., Bond, J., Butnor, K., Heintz, N., Gruber, A., Vacek, P., and Mossman, B.T. (2005) Gene Expression Profiles Reveal Increased mCLCA3 Expression and Mucus Metaplasia in a Murine Model of Asbestos-Induced Fibrogenesis. Am J Pathol. 2005 Nov;167(5):1243-56.
  • Ramos-Nino, ME, Vianale, G., Sabo-Atwood, T., Mutti, L., and Mossman, B.T. (2004) Human Mesothelioma Cells Exhibit Tumor Cell-Specific Differences in Phosphatidylinositol 3-kinase/AKT Activity that Predict the Efficacy of Onconase. Molecular Cancer Therapeutics 2005; 4(5).
  • Sabo-Attwood, T., Kroll, KJ, and Denslow, N.D. (2004) Differential Expression of Largemouth Bass Estrogen Receptor Isotypes Alpha, Beta, and Gamma By Estradiol. Molecular and Cellular Endocrinology 218, 107-118.
  • Larkin, P., Sabo-Attwood, T., Kelso, J., and Denslow, ND. (2003) Analysis of gene expression profiles in largemouth bass exposed to the endogenous hormone, estradiol, and the environmental contaminants, nonylphenol, and p, p’-DDE. EcoToxicology 12, 463-468.
  • Larkin, P., Sabo-Attwood, T., Kelso, J., and Denslow, N. (2002) Gene expression analysis of largemouth bass to estradiol, nonylphenol, and p,p’-DDE. Comparative Biochemistry and Physiology Special Issue, Functional Genomics, 133, 543-557.
  • Sabo-Attwood, T., Larkin, P., Kelso, J., and Denslow, N.D. (2002) Gene expression profiles of largemouth bass exposed to nonylphenol and ICI 182,780. Endocrine Disruptors: Mechanisms and Impacts, International Congress on the Biology of Fish, 17-28.

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