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About the Risk Assessment Core

The Analytical Toxicology Core Laboratory (ATCL) at the University of Florida provides

comprehensive analytical support to on-campus and off-campus researchers requiring

qualitative and/or quantitative chemical analysis to meet study objectives. Equipped with

state-of- the-art instrumentation and staffed with personnel experienced in handling

complex biological tissues, the ATCL is a resource for method development, as well as

for routine analyses that include a wide range of chemicals.

The ATCL serves a broad array of clients, including UF investigators from the colleges of

Medicine, Nursing, Pharmacy, Veterinary Medicine, Engineering, Liberal Arts and

Sciences, and the Institute of Food & Agricultural Sciences (IFAS). Off campus clients

have included investigators at other universities, law enforcement and legal firms, and

public and private companies, including both large and small pharmaceutical companies.

Despite the laboratory name, the focus is not exclusively on toxic substances, and the

laboratory supports a wide range of biomedical and nutritional research. In addition to

analytical support for preclinical and clinical trials, the ATCL has also handled numerous

analytes in human and animal studies for a variety of drugs, environmental

contaminants, and endogenous biochemical species, along with their respective

metabolites. In addition to research support, the ATCL has conducted stability studies

and provided external validation for pharmaceutical preparations and acted as a

resource for drug diversion and/or abuse testing. On request, the ATCL has also

provided analytical assistance to law enforcement for criminal investigations. The

laboratory has recently expanded its capabilities to include lipidomics and non-targeted

analyses.

Located within the Center for Environmental and Human Toxicology, under the

technical direction of Dr. Viet Dang and Dr. Matthew Booth, the ATCL is a non-profit

service activity of the University of Florida.