The ATCL has a variety of analytical instruments available to meet client needs.
Currently available
Agilent 7890/7000C GC-MS/MS
Customized method development for analytical toxicology screening and quantitative methods is performed on this instrument. We use this instrument for analysis of organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), fatty acids (FAME), and other small molecules. In multiple reaction monitoring (MRM) scan, the system can provide sub-nanogram quantity of analytes under optimal conditions.
AB SCIEX 6500 QTRAP LC-MS/MS
A hybrid triple quadrupole ion trap mass spectrometer, designed to perform quantitative analysis of compounds by using Multiple Reaction Monitoring scans (MRM). It is coupled to a shimadzu Nexera X2 ultra high-performance liquid chromatograph (UHPLC) equipped with a rack changer for either 96 or 384 sample plates that allows to run from one single to hundreds of samples in an automated high-throughput workflow. Due to its unique capabilities, our system allows the analysis of multiple analytes at the same time within the same sample with great accuracy, sensitivity, and short analysis time. It is also equipped with a SelexIon module that helps to separate isobaric species from complex mixtures and reduces matrix effects, enhancing the overall sensitivity of the analysis. We have run a wide variety of applications including PFAS, hydroxylated PAHs, polar pesticides and their metabolites, short chain fatty acids, pharmaceuticals, algal toxins and microcystins, isoflavones, steroid hormones, thyroid hormones, cannabinoids and metabolites, and lipidomics analysis (1300+ species); with often limits of detection that range of nanograms to picograms levels. These are developed assays and we have the potential to develop a method to fit your analytes of interest and needs.
Agilent 7900 ICP/MS
This instrument is used for analysis of minor and trace metals, providing detection down to the sub-parts-per-billion range. A variety of sample matrices are tested, including plant and animal tissues, cell cultures and growth media, sediments as well as water and wastewater.
