Eric S. Sobel, M.D., Ph.D.

Associate Professor, Program Directorericsobel

Office: Rheumatology & Clinical Immunology

Phone: (352) 265-0139


Current Research Interests

  • Mouse models of systemic autoimmunity.


  • Ph.D., Biochemistry, Case Western Reserve University.
  • M.D., Case Western Reserve University.

Selected Publications

  • Sobel ES, Kakkanaiah M, Cohen PL, and Eisenberg RA. Co-infusion of normal bone marrow partially corrects the gld T-cell defect. Evidence for an intrinsic and extrinsic role for Fas ligand. J. Immunol. 154(1): 459-464, 1995.
  • Hanley GA., Schiffenbauer J, and Sobel ES.. Class II haplotype differentially regulates immune response in HgCl2-treated mice. Clin. Immunol. Immunopathol., 84:328-37, 1997.
  • Hanley, G.A., Schiffenbauer J., and Sobel E.S. Resistance to HgCl2-induced autoimmunity in haplotype-heterozygous mice is an intrinsic property of B cells. J. Immunol. 161:1778-1785. 1998.
  • Sobel ES, Mohan C, Morel L, Schiffenbauer J, and Wakeland E K.. Genetic dissection of SLE pathogenesis: adoptive transfer of Sle1 mediates the loss of tolerance by bone-marrow-derived B cells. J. Immunol. 162: 2415-2421, 1999
  • Khaled, A.R., Butfiloski, E.J., Villas B., Sobel, E.S., and Schiffenbauer, J. Aberrant expression of the NK-κB and IκB proteins in B cells from viable motheaten mice. Autoimmun. 30:115-128, 1999.