J.M. Patel, M.D., Ph.D.

Professor of MedicineJMPatel

Office:

Phone: (352) 273-8740

Email: pateljm@medicine.ufl.edu

Current Research Interests

  • Development of a rat model of lung transplantation
  • Biology and toxicology of nitric oxide (NO)
  • Regulation of lung endothelial cell NO synthase (eNOS)
  • Pulmonary system toxicology of drugs and environmental chemicals
  • Role of Thioredoxin in Lung Allograft Inju

Education

  • Ph.D. in Biochemistry, Marathwada University, Aurangabad 1973
  • M.S. Master of Science in Biochemistry, Marathwada University, Aurangabad 1971

Selected Publications

  • “Autoinhibitory Doamin Fragment of Endothelial NOS Enhances Pulmonary Artery Vasorelaxation by NO/cGMP Pathway”.Hanbo Hu, M. Xin, L.L. Belayev, J.L. Zhang, E.R. Block, and J.M. PatelAm. J. Physdiol Lung Cell Mol. Physiol.286: L1066-L1074, 2004.
  • “Nitric Oxide-Modulated Marker Gene Expression of Signal Transduction Pathways in Lung Endothelial Cells” Liuzhe Li, J.L. Zhang, E.R. Block, and J.M. PatelNitric Oxide. In Press.
  • “Nitric Oxide-Induced Persistent Inhibition and Nitrosylation of Active Site Cysteine Residues of Mitochondrial Cytochrome c Oxidase in Lung Endothelial Cells”. J.L. Zhang, Bilian Jin, Liuzhe Li, E.R. Block, and J.M. PatelAm.J.Physiol Cell Physiol. In Press