Nancy D Denslow

Nancy D Denslow,

Professor

Department: Department of Physiological Sciences
Business Phone: (352) 294-4642
Business Email: ndenslow@ufl.edu

Accomplishments

Distinguished Faculty Fellow
2020 · University of Florida Water Institute
Term Research Professor
2017-2020 · University of Florida
Founders Award
2016 · Society of Environmental Toxicology and Chemistry
Zoetis Award for Veterinary Research Excellence
2014 · University of Florida College of Veterinary Medicine
Blue Ribbon Scientific Advisory Panel
2009-2012 · California State Water Resources Control Board
Term Research Professor
2009-2012 · University of Florida
Pfizer Award for Research Excellence
2007 · College of Veterinary Medicine, University of Florida

Teaching Profile

Courses Taught
2013-2025
BCH5413 Mammalian Molecular Biology and Genetics
2013-2014,2016-2021,2020-2025,2023-2025
BCH4905 Biochemistry Senior Research
2006-2007,2009-2012,2011-2017,2014-2020,2016-2023
VME6934 Topics in Veterinary Medical Sciences
2010,2019-2020
VME6905 Problems in Veterinary Medical Sciences
2015-2016,2018-2021,2020-2024
GMS6009 Principles of Drug Action and Therapeutics
2018
CHM7979 Advanced Research
2018
PHC7980 Research for Doctoral Dissertation
2018
FAS7980 Research for Doctoral Dissertation
2018
ENV7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2018
VME7980 Research for Doctoral Dissertation
2006,2016-2017
VME6932 Seminar in Physiological Sciences
2013,2015
GMS7593 Topics in Pharmacology and Toxicology
2010
IDH4917 Undergrad Research
2008-2009
VME6607 Human Health Risk Assessment

Research Profile

Dr. Denslow’s research involves developing and using molecular biomarkers to evaluate changes in gene expression depending on stress or exposure to contaminants. Molecular approaches including transcriptomics, proteomics, and lipidomics were developed for several non-model species, including fish, gastropods, and coral. Fish swim in waters that are contaminated by superfund chemicals and emerging contaminants of concern and, thus, provide a direct measure of effects of the contaminants in vertebrates. Many of the chemicals behave as endocrine disruptors and, in particular, as estrogen mimics. To better study the direct effects of these contaminants on reproduction, three largemouth bass estrogen receptors (alpha and two beta-like subtypes) were isolated, sequenced, and integrated into expression assays. The receptors appear to bind and are activated differentially by organochlorine pesticides. In addition, the tissue expression patterns are different for the three receptors. Herbicides, such as glyphosate, are high volume use and affect the immune systems and kidney function of largemouth bass and manatees. Better monitoring of these herbicides is required.

Areas of Interest
  • OMICS technologies
  • endocrine disruption
  • non model species

Publications

Academic Articles
2024
An XAS study of Hg(II) sorption to Al-based drinking water treatment residuals.
Chemosphere. 349 [DOI] 10.1016/j.chemosphere.2023.140922. [PMID] 38101479.
2024
Effects of the organochlorine pesticide metabolite p,p’-DDE on the gastrointestinal lipidome in fish: A novel toxicity pathway for a legacy pollutant.
Environmental pollution (Barking, Essex : 1987). 363(Pt 2) [DOI] 10.1016/j.envpol.2024.125191. [PMID] 39454813.
2024
Enrichment of Bioactive Lipids in Urinary Extracellular Vesicles and Evidence of Apoptosis in Kidneys of Hypertensive Diabetic Cathepsin B Knockout Mice after Streptozotocin Treatment.
Biomedicines. 12(5) [DOI] 10.3390/biomedicines12051038. [PMID] 38791000.
2024
Evaluating drinking water treatment residuals as an in-situ capping material for metal-contaminated sediments.
Chemosphere. 368 [DOI] 10.1016/j.chemosphere.2024.143712. [PMID] 39521291.
2024
Extracellular vesicles from BALF of pediatric cystic fibrosis and asthma patients increase epithelial sodium channel activity in small airway epithelial cells.
Biochimica et biophysica acta. Biomembranes. 1866(1) [DOI] 10.1016/j.bbamem.2023.184219. [PMID] 37634857.
2024
In vitro impacts of glyphosate on manatee lymphocytes.
Environment international. 193 [DOI] 10.1016/j.envint.2024.109054. [PMID] 39537518.
2024
Lipidomics and plasma hormone analysis differentiate reproductive and pregnancy statuses in Florida manatees (Trichechus manatus latirostris).
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 50 [DOI] 10.1016/j.cbd.2024.101231. [PMID] 38643744.
2024
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.
Nature methods. 21(7):1349-1363 [DOI] 10.1038/s41592-024-02298-3. [PMID] 38849569.
2023
Assessment of lipids and adrenal hormones in the Florida manatee (Trichechus manatus latirostris) from different habitats.
General and comparative endocrinology. 337 [DOI] 10.1016/j.ygcen.2023.114250. [PMID] 36858274.
2023
Dapagliflozin Treatment Augments Bioactive Phosphatidylethanolamine Concentrations in Kidney Cortex Membrane Fractions of Hypertensive Diabetic db/db Mice and Alters the Density of Lipid Rafts in Mouse Proximal Tubule Cells.
International journal of molecular sciences. 24(2) [DOI] 10.3390/ijms24021408. [PMID] 36674924.
2023
Decreased MARCKS Protein Expression in Kidney Cortex Membrane Fractions of Cathepsin B Knockout Mice Is Associated with Reduced Lysophosphatidylcholine and Protein Kinase C Activity.
Biomedicines. 11(5) [DOI] 10.3390/biomedicines11051489. [PMID] 37239160.
2023
Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis.
Clinical immunology (Orlando, Fla.). 248 [DOI] 10.1016/j.clim.2022.109213. [PMID] 36566913.
2023
Systematic assessment of long-read RNA-seq methods for transcript identification and quantification.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.07.25.550582. [PMID] 37546854.
2023
Trace elements and lipidomic datasets of stranding samples in the blubber of Turpsios truncatus from the Yucatan coast: Association with biological features.
Data in brief. 49 [DOI] 10.1016/j.dib.2023.109374. [PMID] 37520656.
2022
C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C Pathway.
International journal of molecular sciences. 23(22) [DOI] 10.3390/ijms232213959. [PMID] 36430437.
2022
Endocrine, immune and renal toxicity in male largemouth bass after chronic exposure to glyphosate and Rodeo®.
Aquatic toxicology (Amsterdam, Netherlands). 246 [DOI] 10.1016/j.aquatox.2022.106142. [PMID] 35306440.
2022
Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice.
Biomolecules. 13(1) [DOI] 10.3390/biom13010066. [PMID] 36671451.
2022
Increased levels of perfluorooctanesulfonic acid (PFOS) during Hurricane Dorian on the east coast of Florida.
Environmental research. 208 [DOI] 10.1016/j.envres.2021.112635. [PMID] 34990607.
2022
Lipid Profiles of Urinary Extracellular Vesicles Released during the Inactive and Active Phases of Aged Male Mice with Spontaneous Hypertension.
International journal of molecular sciences. 23(23) [DOI] 10.3390/ijms232315397. [PMID] 36499728.
2022
Physical Evidence of Oil Uptake and Toxicity Assessment of Amphiphilic Grafted Nanoparticles Used as Oil Dispersants.
Environmental science & technology. 56(12):7917-7923 [DOI] 10.1021/acs.est.1c08564. [PMID] 35580268.
2022
Putative high-level toxicity pathways based on evidence of brevetoxin immunotoxicity in marine fauna.
Aquatic toxicology (Amsterdam, Netherlands). 252 [DOI] 10.1016/j.aquatox.2022.106298. [PMID] 36162204.
2022
Towards regulation of Endocrine Disrupting chemicals (EDCs) in water resources using bioassays – A guide to developing a testing strategy.
Environmental research. 205 [DOI] 10.1016/j.envres.2021.112483. [PMID] 34863984.
2022
Trace element and lipidomic analysis of bottlenose dolphin blubber from the Yucatan coast: Lipid composition relationships.
Chemosphere. 299 [DOI] 10.1016/j.chemosphere.2022.134353. [PMID] 35314180.
2021
A Screening Approach for the Selection of Drinking Water Treatment Residuals for Their Introduction to Marine Systems.
Environmental toxicology and chemistry. 40(4):1194-1203 [DOI] 10.1002/etc.4950. [PMID] 33270295.
2021
Acute and Chronic Toxicity Testing of Drinking Water Treatment Residuals in Freshwater Systems.
Environmental toxicology and chemistry. 40(7):2005-2014 [DOI] 10.1002/etc.5061. [PMID] 33818832.
2021
Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients.
Journal of neurotrauma. 38(1):1-43 [DOI] 10.1089/neu.2020.7332. [PMID] 33115334.
2021
Chronic exposure to glyphosate in Florida manatee.
Environment international. 152 [DOI] 10.1016/j.envint.2021.106493. [PMID] 33740675.
2021
Estrogenicity of chemical mixtures revealed by a panel of bioassays.
The Science of the total environment. 785 [DOI] 10.1016/j.scitotenv.2021.147284. [PMID] 33957588.
2021
Impact of bisphenol-A and synthetic estradiol on brain, behavior, gonads and sex hormones in a sexually labile coral reef fish.
Hormones and behavior. 136 [DOI] 10.1016/j.yhbeh.2021.105043. [PMID] 34507054.
2021
Increased endothelial sodium channel activity by extracellular vesicles in human aortic endothelial cells: putative role of MLP1 and bioactive lipids.
American journal of physiology. Cell physiology. 321(3):C535-C548 [DOI] 10.1152/ajpcell.00092.2020. [PMID] 34288724.
2021
Investigating an increase in Florida manatee mortalities using a proteomic approach.
Scientific reports. 11(1) [DOI] 10.1038/s41598-021-83687-y. [PMID] 33608577.
2021
Lipidomics reveals multiple stressor effects (temperature × mitochondrial toxicant) in the zebrafish embryo toxicity test.
Chemosphere. 264(Pt 1) [DOI] 10.1016/j.chemosphere.2020.128472. [PMID] 33039916.
2021
Mussels drive polychlorinated biphenyl (PCB) biomagnification in a coastal food web.
Scientific reports. 11(1) [DOI] 10.1038/s41598-021-88684-9. [PMID] 33911140.
2021
Novel effective mosquito larvicide DL-methionine: Lack of toxicity to non-target aquatic organisms.
Ecotoxicology and environmental safety. 213 [DOI] 10.1016/j.ecoenv.2021.112013. [PMID] 33601173.
2021
Practical Euthanasia Method for Common Sea Stars (Asterias rubens) That Allows for High-Quality RNA Sampling.
Animals : an open access journal from MDPI. 11(7) [DOI] 10.3390/ani11071847. [PMID] 34206249.
2021
Tempol Alters Urinary Extracellular Vesicle Lipid Content and Release While Reducing Blood Pressure during the Development of Salt-Sensitive Hypertension.
Biomolecules. 11(12) [DOI] 10.3390/biom11121804. [PMID] 34944449.
2021
Untargeted lipidomics reveals the toxicity of bisphenol A bis(3-chloro-2- hydroxypropyl) ether and bisphenols A and F in zebrafish liver cells.
Ecotoxicology and environmental safety. 219 [DOI] 10.1016/j.ecoenv.2021.112311. [PMID] 33993092.
2020
Antineoplastic Agents: Environmental Prevalence and Adverse Outcomes in Aquatic Organisms.
Environmental toxicology and chemistry. 39(5):967-985 [DOI] 10.1002/etc.4687. [PMID] 32266737.
2020
Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis.
Proceedings of the National Academy of Sciences of the United States of America. 117(9):4642-4652 [DOI] 10.1073/pnas.1919563117. [PMID] 32071231.
2020
Ecotoxico-lipidomics: An emerging concept to understand chemical-metabolic relationships in comparative fish models.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100742. [PMID] 32956922.
2020
Investigating the gene expression profiles of rehabilitated Florida manatees (Trichechus manatus latirostris) following red tide exposure.
PloS one. 15(7) [DOI] 10.1371/journal.pone.0234150. [PMID] 32614830.
2020
Organochlorine pesticides: Agrochemicals with potent endocrine-disrupting properties in fish.
Molecular and cellular endocrinology. 507 [DOI] 10.1016/j.mce.2020.110764. [PMID] 32112812.
2020
Quantification of steroid hormones in low volume plasma and tissue homogenates of fish using LC-MS/MS.
General and comparative endocrinology. 296 [DOI] 10.1016/j.ygcen.2020.113543. [PMID] 32598883.
2020
Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the ChascomĂşs chained shallow lakes system (Argentina).
The Science of the total environment. 743 [DOI] 10.1016/j.scitotenv.2020.140401. [PMID] 32653700.
2020
Steroidogenic acute regulatory protein transcription is regulated by estrogen receptor signaling in largemouth bass ovary.
General and comparative endocrinology. 286 [DOI] 10.1016/j.ygcen.2019.113300. [PMID] 31678557.
2020
The organochlorine pesticide toxaphene reduces non-mitochondrial respiration and induces heat shock protein 70 expression in early-staged zebrafish (Danio rerio).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 228 [DOI] 10.1016/j.cbpc.2019.108669. [PMID] 31712185.
2020
Toxicity assessment of a novel oil dispersant based on silica nanoparticles using Fathead minnow.
Aquatic toxicology (Amsterdam, Netherlands). 229 [DOI] 10.1016/j.aquatox.2020.105653. [PMID] 33080536.
2020
Transcriptome and physiological effects of toxaphene on the liver-gonad reproductive axis in male and female largemouth bass (Micropterus salmoides).
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 36 [DOI] 10.1016/j.cbd.2020.100746. [PMID] 32992212.
2020
Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish.
General and comparative endocrinology. 286 [DOI] 10.1016/j.ygcen.2019.113325. [PMID] 31733209.
2019
Blood Transcriptomics Analysis of Fish Exposed to Perfluoro Alkyls Substances: Assessment of a Non-Lethal Sampling Technique for Advancing Aquatic Toxicology Research.
Environmental science & technology. 53(3):1441-1452 [DOI] 10.1021/acs.est.8b03603. [PMID] 30572700.
2019
Computational in Vitro Toxicology Uncovers Chemical Structures Impairing Mitochondrial Membrane Potential.
Journal of chemical information and modeling. 59(2):702-712 [DOI] 10.1021/acs.jcim.8b00433. [PMID] 30645939.
2019
Effects of Chlorpyrifos on Cholinesterase and Serine Lipase Activities and Lipid Metabolism in Brains of Rainbow Trout (Oncorhynchus mykiss).
Toxicological sciences : an official journal of the Society of Toxicology. 172(1):146-154 [DOI] 10.1093/toxsci/kfz167. [PMID] 31359069.
2019
Lipidomic analysis of urinary exosomes from hereditary α-tryptasemia patients and healthy volunteers.
FASEB bioAdvances. 1(10):624-638 [DOI] 10.1096/fba.2019-00030. [PMID] 31803861.
2018
Activated carbon as a means of limiting bioaccumulation of organochlorine pesticides, triclosan, triclocarban, and fipronil from sediments rich in organic matter.
Chemosphere. 197:627-633 [DOI] 10.1016/j.chemosphere.2018.01.062. [PMID] 29407826.
2018
Comparative toxicity of three phenolic compounds on the embryo of fathead minnow, Pimephales promelas.
Aquatic toxicology (Amsterdam, Netherlands). 201:66-72 [DOI] 10.1016/j.aquatox.2018.05.024. [PMID] 29879596.
2018
Early phosphoproteomic changes for adverse outcome pathway development in the fathead minnow (Pimephales promelas) brain.
Scientific reports. 8(1) [DOI] 10.1038/s41598-018-28395-w. [PMID] 29977039.
2018
Estrogen signaling through both membrane and nuclear receptors in the liver of fathead minnow.
General and comparative endocrinology. 257:50-66 [DOI] 10.1016/j.ygcen.2017.07.019. [PMID] 28733229.
2018
Human exposure to polycyclic aromatic hydrocarbons: Metabolomics perspective.
Environment international. 119:466-477 [DOI] 10.1016/j.envint.2018.07.017. [PMID] 30032012.
2018
Hydrogen Peroxide Stimulates Exosomal Cathepsin B Regulation of the Receptor for Advanced Glycation End-Products (RAGE).
Journal of cellular biochemistry. 119(1):599-606 [DOI] 10.1002/jcb.26219. [PMID] 28618037.
2018
In Silico Computational Transcriptomics Reveals Novel Endocrine Disruptors in Largemouth Bass ( Micropterus salmoides).
Environmental science & technology. 52(13):7553-7565 [DOI] 10.1021/acs.est.8b02805. [PMID] 29878769.
2018
Linking in vitro estrogenicity to adverse effects in the inland silverside (Menidia beryllina).
Environmental toxicology and chemistry. 37(3):884-892 [DOI] 10.1002/etc.4024. [PMID] 29091346.
2018
Tissue-Based Mapping of the Fathead Minnow (Pimephales promelas) Transcriptome and Proteome.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00611. [PMID] 30459712.
2018
Toward an adverse outcome pathway for impaired growth: Mitochondrial dysfunction impairs growth in early life stages of the fathead minnow (Pimephales promelas).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 209:46-53 [DOI] 10.1016/j.cbpc.2018.03.009. [PMID] 29625345.
2017
Computational analysis of the ToxCast estrogen receptor agonist assays to predict vitellogenin induction by chemicals in male fish.
Environmental toxicology and pharmacology. 53:177-183 [DOI] 10.1016/j.etap.2017.05.015. [PMID] 28645054.
2017
Current limitations and recommendations to improve testing for the environmental assessment of endocrine active substances.
Integrated environmental assessment and management. 13(2):302-316 [DOI] 10.1002/ieam.1862. [PMID] 27791330.
2017
Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish.
Toxicological sciences : an official journal of the Society of Toxicology. 156(2):344-361 [DOI] 10.1093/toxsci/kfw257. [PMID] 28201806.
2017
Effect-based tools for monitoring estrogenic mixtures: Evaluation of five in vitro bioassays.
Water research. 110:378-388 [DOI] 10.1016/j.watres.2016.10.062. [PMID] 27836174.
2017
Gene Expression Profiling in Fish Toxicology: A Review.
Reviews of environmental contamination and toxicology. 241:1-38 [DOI] 10.1007/398_2016_10. [PMID] 27464848.
2017
How consistent are we? Interlaboratory comparison study in fathead minnows using the model estrogen 17α-ethinylestradiol to develop recommendations for environmental transcriptomics.
Environmental toxicology and chemistry. 36(10):2614-2623 [DOI] 10.1002/etc.3799. [PMID] 28316117.
2017
Influence of the Gastrointestinal Environment on the Bioavailability of Ethinyl Estradiol Sorbed to Single-Walled Carbon Nanotubes.
Environmental science & technology. 51(2):948-957 [DOI] 10.1021/acs.est.6b04728. [PMID] 27977933.
2017
Lipidomic and proteomic analysis of exosomes from mouse cortical collecting duct cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(12):5399-5408 [DOI] 10.1096/fj.201700417R. [PMID] 28821634.
2017
Neuroendocrine disruption of organizational and activational hormone programming in poikilothermic vertebrates.
Journal of toxicology and environmental health. Part B, Critical reviews. 20(5):276-304 [DOI] 10.1080/10937404.2017.1370083. [PMID] 28895797.
2017
Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval zebrafish (Danio rerio).
Toxicology and applied pharmacology. 327:30-38 [DOI] 10.1016/j.taap.2017.04.024. [PMID] 28450151.
2017
Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances.
Integrated environmental assessment and management. 13(2):267-279 [DOI] 10.1002/ieam.1885. [PMID] 28127947.
2016
A tiered, integrated biological and chemical monitoring framework for contaminants of emerging concern in aquatic ecosystems.
Integrated environmental assessment and management. 12(3):540-7 [DOI] 10.1002/ieam.1702. [PMID] 26426153.
2016
Active Sampling Device for Determining Pollutants in Surface and Pore Water – the In Situ Sampler for Biphasic Water Monitoring.
Scientific reports. 6 [DOI] 10.1038/srep21886. [PMID] 26905924.
2016
Bioaccumulation of Legacy and Emerging Organochlorine Contaminants in Lumbriculus variegatus.
Archives of environmental contamination and toxicology. 71(1):60-9 [DOI] 10.1007/s00244-016-0264-x. [PMID] 26833202.
2016
Ecotoxicogenomics: Microarray interlaboratory comparability.
Chemosphere. 144:193-200 [DOI] 10.1016/j.chemosphere.2015.08.019. [PMID] 26363320.
2016
Footprints of Urban Micro-Pollution in Protected Areas: Investigating the Longitudinal Distribution of Perfluoroalkyl Acids in Wildlife Preserves.
PloS one. 11(2) [DOI] 10.1371/journal.pone.0148654. [PMID] 26909512.
2016
High contaminant loads in Lake Apopka’s riparian wetland disrupt gene networks involved in reproduction and immune function in largemouth bass.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:140-150 [DOI] 10.1016/j.cbd.2016.06.003. [PMID] 27397556.
2016
Molecular impacts of perfluorinated chemicals (PFASs) in the liver and testis of male largemouth bass (Micropterus salmoides) in Minnesota Lakes.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:129-139 [DOI] 10.1016/j.cbd.2016.02.001. [PMID] 26907229.
2016
Screening for Endocrine Activity in Water Using Commercially-available In Vitro Transactivation Bioassays.
Journal of visualized experiments : JoVE. (118) [DOI] 10.3791/54725. [PMID] 28060336.
2016
The influence of breeding strategy, reproductive stage, and tissue type on transcript variability in fish.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 19:151-158 [DOI] 10.1016/j.cbd.2016.05.005. [PMID] 27325421.
2016
Tissue distribution of organochlorine pesticides in largemouth bass (Micropterus salmoides) from laboratory exposure and a contaminated lake.
Environmental pollution (Barking, Essex : 1987). 216:877-883 [DOI] 10.1016/j.envpol.2016.06.061. [PMID] 27394080.
2016
Transcriptional networks associated with the immune system are disrupted by organochlorine pesticides in largemouth bass (Micropterus salmoides) ovary.
Aquatic toxicology (Amsterdam, Netherlands). 177:405-16 [DOI] 10.1016/j.aquatox.2016.06.009. [PMID] 27391359.
2016
Transcriptomic and physiological changes in Eastern Mosquitofish (Gambusia holbrooki) after exposure to progestins and anti-progestagens.
Aquatic toxicology (Amsterdam, Netherlands). 179:8-17 [DOI] 10.1016/j.aquatox.2016.08.002. [PMID] 27541482.
2016
Transcriptomics analysis and hormonal changes of male and female neonatal rats treated chronically with a low dose of acrylamide in their drinking water.
Toxicology reports. 3:414-426 [DOI] 10.1016/j.toxrep.2016.03.009. [PMID] 28959563.
2015
Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology.
Chemosphere. 120:764-77 [DOI] 10.1016/j.chemosphere.2014.09.068. [PMID] 25439131.
2015
Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish.
Chemosphere. 120:778-92 [DOI] 10.1016/j.chemosphere.2014.10.006. [PMID] 25456049.
2015
Developmental abnormalities and differential expression of genes induced in oil and dispersant exposed Menidia beryllina embryos.
Aquatic toxicology (Amsterdam, Netherlands). 168:60-71 [DOI] 10.1016/j.aquatox.2015.09.012. [PMID] 26448268.
2015
Examination of Single-Walled Carbon Nanotubes Uptake and Toxicity from Dietary Exposure: Tracking Movement and Impacts in the Gastrointestinal System.
Nanomaterials (Basel, Switzerland). 5(2):1066-1086 [DOI] 10.3390/nano5021066. [PMID] 28347052.
2015
Interlaboratory comparison of in vitro bioassays for screening of endocrine active chemicals in recycled water.
Water research. 83:303-9 [DOI] 10.1016/j.watres.2015.06.050. [PMID] 26177482.
2015
Potential estrogenic effects of wastewaters on gene expression in Pimephales promelas and fish assemblages in streams of southeastern New York.
Environmental toxicology and chemistry. 34(12):2803-15 [DOI] 10.1002/etc.3120. [PMID] 26423596.
2015
Recent advances in proteomics applied to elucidate the role of environmental impacts on human health and organismal function.
Journal of proteome research. 14(1):1-4 [DOI] 10.1021/pr501224f. [PMID] 25751307.
2015
Transcriptional and physiological response of fathead minnows (Pimephales promelas) exposed to urban waters entering into wildlife protected areas.
Environmental pollution (Barking, Essex : 1987). 199:155-65 [DOI] 10.1016/j.envpol.2015.01.021. [PMID] 25656232.
2014
An adaptive, comprehensive monitoring strategy for chemicals of emerging concern (CECs) in California’s Aquatic Ecosystems.
Integrated environmental assessment and management. 10(1):69-77 [DOI] 10.1002/ieam.1483. [PMID] 24129960.
2014
An inter-laboratory study on the variability in measured concentrations of 17β-estradiol, testosterone, and 11-ketotestosterone in white sucker: implications and recommendations.
Environmental toxicology and chemistry. 33(4):847-57 [DOI] 10.1002/etc.2503. [PMID] 24375479.
2014
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays.
Environmental science & technology. 48(3):1940-56 [DOI] 10.1021/es403899t. [PMID] 24369993.
2014
Bmp7 and Lef1 are the downstream effectors of androgen signaling in androgen-induced sex characteristics development in medaka.
Endocrinology. 155(2):449-62 [DOI] 10.1210/en.2013-1507. [PMID] 24248458.
2014
Control of transcriptional repression of the vitellogenin receptor gene in largemouth bass (Micropterus salmoides) by select estrogen receptors isotypes.
Toxicological sciences : an official journal of the Society of Toxicology. 141(2):423-31 [DOI] 10.1093/toxsci/kfu145. [PMID] 25061109.
2014
Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study.
The Science of the total environment. 484:379-89 [DOI] 10.1016/j.scitotenv.2013.08.034. [PMID] 24050789.
2014
Dietary exposure of 17-alpha ethinylestradiol modulates physiological endpoints and gene signaling pathways in female largemouth bass (Micropterus salmoides).
Aquatic toxicology (Amsterdam, Netherlands). 156:148-60 [DOI] 10.1016/j.aquatox.2014.08.008. [PMID] 25203422.
2014
Differential effects and potential adverse outcomes of ionic silver and silver nanoparticles in vivo and in vitro.
Environmental science & technology. 48(8):4546-55 [DOI] 10.1021/es4042258. [PMID] 24684273.
2014
Exposure to paper mill effluent at a site in North Central Florida elicits molecular-level changes in gene expression indicative of progesterone and androgen exposure.
PloS one. 9(9) [DOI] 10.1371/journal.pone.0106644. [PMID] 25198161.
2014
Gene networks and toxicity pathways induced by acute cadmium exposure in adult largemouth bass (Micropterus salmoides).
Aquatic toxicology (Amsterdam, Netherlands). 152:186-94 [DOI] 10.1016/j.aquatox.2014.04.004. [PMID] 24794047.
2014
Methylmercury-induced changes in gene transcription associated with neuroendocrine disruption in largemouth bass (Micropterus salmoides).
General and comparative endocrinology. 203:215-224 [DOI] 10.1016/j.ygcen.2014.03.029. [PMID] 24694518.
2014
Molecular Signature and Dna Damage Pathways Altered in Male Largemouth Bass (Micropterus Salmoides) By a Single Dose of Benzene and Trichloroethylene
Environmental and Molecular Mutagenesis. 55(1)
2014
Transcriptomic effects-based monitoring for endocrine active chemicals: assessing relative contribution of treated wastewater to downstream pollution.
Environmental science & technology. 48(4):2385-94 [DOI] 10.1021/es404027n. [PMID] 24409827.
2014
Transcriptomics of the fetal hypothalamic response to brachiocephalic occlusion and estradiol treatment.
Physiological genomics. 46(14):523-32 [DOI] 10.1152/physiolgenomics.00186.2013. [PMID] 24824211.
2013
A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture.
PloS one. 8(11) [DOI] 10.1371/journal.pone.0081253. [PMID] 24260565.
2013
Chronic nanoparticulate silver exposure results in tissue accumulation and transcriptomic changes in zebrafish.
Aquatic toxicology (Amsterdam, Netherlands). 130-131:192-200 [DOI] 10.1016/j.aquatox.2013.01.010. [PMID] 23416412.
2013
Custom microarray construction and analysis for determining potential biomarkers of subchronic androgen exposure in the Eastern Mosquitofish (Gambusia holbrooki).
BMC genomics. 14 [DOI] 10.1186/1471-2164-14-660. [PMID] 24074126.
2013
Designing monitoring programs for chemicals of emerging concern in potable reuse–what to include and what not to include?
Water science and technology : a journal of the International Association on Water Pollution Research. 67(2):433-9 [DOI] 10.2166/wst.2012.520. [PMID] 23168646.
2013
Different Profiles of Csf and Serum Biomarkers of Cns Injury in Preclinical Models of Traumatic Brain Injury and Neurotoxicity
Journal of Neurotrauma. 30:A130-A131
2013
Effects of 17β-trenbolone on Eastern and Western mosquitofish (Gambusia holbrooki and G. affinis) anal fin growth and gene expression patterns.
Aquatic toxicology (Amsterdam, Netherlands). 128-129:163-70 [DOI] 10.1016/j.aquatox.2012.12.007. [PMID] 23314276.
2013
Functional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeast.
Toxicological sciences : an official journal of the Society of Toxicology. 132(2):347-58 [DOI] 10.1093/toxsci/kft018. [PMID] 23358190.
2013
Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides).
PloS one. 8(3) [DOI] 10.1371/journal.pone.0059093. [PMID] 23527095.
2013
Gene expression of fathead minnows (Pimephales promelas) exposed to two types of treated municipal wastewater effluents.
Environmental science & technology. 47(19):11268-77 [DOI] 10.1021/es401942n. [PMID] 23919544.
2013
Gene expression profiling in the ovary of Queen conch (Strombus gigas) exposed to environments with high tributyltin in the British Virgin Islands.
The Science of the total environment. 449:52-62 [DOI] 10.1016/j.scitotenv.2013.01.028. [PMID] 23410894.
2013
Genomics of the fetal hypothalamic cellular response to transient hypoxia: endocrine, immune, and metabolic responses.
Physiological genomics. 45(13):521-7 [DOI] 10.1152/physiolgenomics.00005.2013. [PMID] 23653468.
2013
Sexually dimorphic transcriptomic responses in the teleostean hypothalamus: a case study with the organochlorine pesticide dieldrin.
Neurotoxicology. 34:105-17 [DOI] 10.1016/j.neuro.2012.09.012. [PMID] 23041725.
2013
Transcriptional signature of progesterone in the fathead minnow ovary (Pimephales promelas).
General and comparative endocrinology. 192:159-69 [DOI] 10.1016/j.ygcen.2013.06.008. [PMID] 23796460.
2013
Using Omics Technologies To Unravel Mechanisms of Toxicity From Endocrine Disruptors in Aquatic Species
Toxicology Letters. 221 [DOI] 10.1016/j.toxlet.2013.06.227.
2012
A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis.
Mutation research. 746(2):151-62 [DOI] 10.1016/j.mrgentox.2011.12.016. [PMID] 22227403.
2012
Advancing the Omics in aquatic toxicology: SETAC North America 31st Annual Meeting.
Ecotoxicology and environmental safety. 76(2):1-2 [DOI] 10.1016/j.ecoenv.2011.11.001. [PMID] 22114953.
2012
Applications for next-generation sequencing in fish ecotoxicogenomics.
Frontiers in genetics. 3 [DOI] 10.3389/fgene.2012.00062. [PMID] 22539934.
2012
Cerebrospinal fluid protein biomarker panel for assessment of neurotoxicity induced by kainic acid in rats.
Toxicological sciences : an official journal of the Society of Toxicology. 130(1):158-67 [DOI] 10.1093/toxsci/kfs224. [PMID] 22790971.
2012
DIGE and iTRAQ as biomarker discovery tools in aquatic toxicology.
Ecotoxicology and environmental safety. 76(2):3-10 [DOI] 10.1016/j.ecoenv.2011.09.020. [PMID] 22056798.
2012
Effects of exposure to the β-blocker propranolol on the reproductive behavior and gene expression of the fathead minnow, Pimephales promelas.
Aquatic toxicology (Amsterdam, Netherlands). 116-117:8-15 [DOI] 10.1016/j.aquatox.2012.03.001. [PMID] 22465857.
2012
Evaluation of water quality threats to the endangered Okaloosa darter (Etheostoma okaloosae) in East Turkey Creek on Eglin Air Force Base.
Aquatic toxicology (Amsterdam, Netherlands). 110-111:177-86 [DOI] 10.1016/j.aquatox.2012.01.007. [PMID] 22326655.
2012
Exploring androgen-regulated pathways in teleost fish using transcriptomics and proteomics.
Integrative and comparative biology. 52(5):695-704 [DOI] 10.1093/icb/ics072. [PMID] 22596056.
2012
Genomics of estradiol-3-sulfate action in the ovine fetal hypothalamus.
Physiological genomics. 44(13):669-77 [DOI] 10.1152/physiolgenomics.00127.2011. [PMID] 22570439.
2012
Glutamatergic Receptors Are Expressed At Pronounced Higher Rate in the Ovine Fetal Hypothalamus Than Pituitary During the Late Gestation Period
Reproduction in Domestic Animals. 47
2012
Identification and transcriptional modulation of the largemouth bass, Micropterus salmoides, vitellogenin receptor during oocyte development by insulin and sex steroids.
Biology of reproduction. 87(3) [PMID] 22786822.
2012
Proteomic expression patterns in fathead minnows exposed to trenbolone and flutamide
Integrative and Comparative Biology. 52(1)
2012
PROTEOMICS AS A TOOL TO STUDY NEUROTOXICITY IN FISH
Integrative and Comparative Biology. 52(1)
2012
Quantitative proteomics in teleost fish: insights and challenges for neuroendocrine and neurotoxicology research.
General and comparative endocrinology. 176(3):314-20 [DOI] 10.1016/j.ygcen.2011.12.006. [PMID] 22202605.
2012
Taking microarrays to the field: differential hepatic gene expression of caged fathead minnows from Nebraska watersheds.
Environmental science & technology. 46(3):1877-85 [DOI] 10.1021/es2039097. [PMID] 22165990.
2011
A computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone.
BMC systems biology. 5 [DOI] 10.1186/1752-0509-5-63. [PMID] 21545743.
2011
Behavioral and genomic impacts of a wastewater effluent on the fathead minnow.
Aquatic toxicology (Amsterdam, Netherlands). 101(1):38-48 [DOI] 10.1016/j.aquatox.2010.08.014. [PMID] 20888052.
2011
Cesium Chloride Gradient Centrifugation Improves the Quality of Total Rna Preparations From the Gastropod Strombus Gigas and the Coral Montastraea Faveolata
Journal of Experimental Marine Biology and Ecology. 402(1-2):43-48 [DOI] 10.1016/j.jembe.2011.03.015.
2011
Characterization of Plasma Vitellogenin and Sex Hormone Concentrations During the Annual Reproductive Cycle of the Endangered Razorback Sucker
North American Journal of Fisheries Management. 31(5):765-781 [DOI] 10.1080/02755947.2011.591231.
2011
Cloning and expression of the translocator protein (18 kDa), voltage-dependent anion channel, and diazepam binding inhibitor in the gonad of largemouth bass (Micropterus salmoides) across the reproductive cycle.
General and comparative endocrinology. 173(1):86-95 [DOI] 10.1016/j.ygcen.2011.04.027. [PMID] 21600210.
2011
Effects of estrogens and antiestrogens on gene expression of fathead minnow (Pimephales promelas) early life stages.
Environmental toxicology. 26(2):195-206 [DOI] 10.1002/tox.20545. [PMID] 19890895.
2011
Gene expression analysis in the thalamus and cerebrum of horses experimentally infected with West Nile virus.
PloS one. 6(10) [DOI] 10.1371/journal.pone.0024371. [PMID] 21991302.
2011
Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury.
Environmental toxicology and chemistry. 30(2):301-8 [DOI] 10.1002/etc.409. [PMID] 21082716.
2011
Impacts of Cyclic Hypoxia On Reproductive and Gene Expression Patterns in the Grass Shrimp: Field Versus Laboratory Comparison
Aquatic Sciences. 73(3):127-141 [DOI] 10.1007/s00027-010-0166-3. [PMID] 21052530.
2011
Investigation of acute nanoparticulate aluminum toxicity in zebrafish.
Environmental toxicology. 26(5):541-51 [DOI] 10.1002/tox.20669. [PMID] 21910207.
2011
Methoxychlor affects multiple hormone signaling pathways in the largemouth bass (Micropterus salmoides) liver.
Aquatic toxicology (Amsterdam, Netherlands). 101(3-4):483-92 [DOI] 10.1016/j.aquatox.2010.12.002. [PMID] 21276474.
2011
Omics in aquatic toxicology: not just another microarray.
Environmental toxicology and chemistry. 30(2):263-4 [DOI] 10.1002/etc.428. [PMID] 21229596.
2011
Species extrapolation for the 21st century.
Environmental toxicology and chemistry. 30(1):52-63 [DOI] 10.1002/etc.382. [PMID] 20963850.
2011
Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus.
Frontiers in physiology. 2 [DOI] 10.3389/fphys.2011.00024. [PMID] 21660287.
2011
Tracheal occlusion modulates the gene expression profile of the medial thalamus in anesthetized rats.
Journal of applied physiology (Bethesda, Md. : 1985). 111(1):117-24 [DOI] 10.1152/japplphysiol.01317.2010. [PMID] 21527662.
2010
Algan/Gan High Electron Mobility Transistor Based Sensors for Environmental and Bio-Applications
Nanoscience and Nanotechnology Letters. 2(2):120-128 [DOI] 10.1166/nnl.2010.1068.
2010
Detection of an endocrine disrupter biomarker, vitellogenin, in largemouth bass serum using AlGaN/GaN high electron mobility transistors
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2010
Effects of acute dieldrin exposure on neurotransmitters and global gene transcription in largemouth bass (Micropterus salmoides) hypothalamus.
Neurotoxicology. 31(4):356-66 [DOI] 10.1016/j.neuro.2010.04.008. [PMID] 20438755.
2010
Environmentally relevant exposure to 17alpha-ethinylestradiol affects the telencephalic proteome of male fathead minnows
. (98):344-353
2010
Environmentally relevant exposure to 17alpha-ethinylestradiol affects the telencephalic proteome of male fathead minnows.
Aquatic toxicology (Amsterdam, Netherlands). 98(4):344-53 [DOI] 10.1016/j.aquatox.2010.03.007. [PMID] 20381887.
2010
Genomic and proteomic responses to environmentally relevant exposures to dieldrin: indicators of neurodegeneration?
Toxicological sciences : an official journal of the Society of Toxicology. 117(1):190-9 [DOI] 10.1093/toxsci/kfq192. [PMID] 20584760.
2010
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook.
Environmental health perspectives. 118(1):1-5 [DOI] 10.1289/ehp.0900985. [PMID] 20056575.
2010
Queen conch (Strombus gigas) testis regresses during the reproductive season at nearshore sites in the Florida Keys.
PloS one. 5(9) [DOI] 10.1371/journal.pone.0012737. [PMID] 20856805.
2010
Rapid dopaminergic modulation of the fish hypothalamic transcriptome and proteome
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2010
Rapid dopaminergic modulation of the fish hypothalamic transcriptome and proteome.
PloS one. 5(8) [DOI] 10.1371/journal.pone.0012338. [PMID] 20808832.
2010
Regulation of steroidogenic acute regulatory protein transcription in largemouth bass by orphan nuclear receptor signaling pathways.
Endocrinology. 151(1):341-9 [DOI] 10.1210/en.2009-0551. [PMID] 19906818.
2009
A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17alpha-ethinylestradiol and 17beta-estradiol.
Toxicological sciences : an official journal of the Society of Toxicology. 109(2):180-92 [DOI] 10.1093/toxsci/kfp069. [PMID] 19357070.
2009
Aquatic contaminants alter genes involved in neurotransmitter synthesis and gonadotropin release in largemouth bass
. (95):1-92
2009
Aquatic contaminants alter genes involved in neurotransmitter synthesis and gonadotropin release in largemouth bass.
Aquatic toxicology (Amsterdam, Netherlands). 95(1):1-9 [DOI] 10.1016/j.aquatox.2009.06.009. [PMID] 19781795.
2009
Characterization of ontogenetic changes in gene expression in the fathead minnow (Pimephales promelas).
Environmental toxicology and chemistry. 28(4):873-80 [DOI] 10.1897/08-213R.1. [PMID] 19391683.
2009
Comparison of comparative genomic hybridization technologies across microarray platforms.
Journal of biomolecular techniques : JBT. 20(2):135-51 [PMID] 19503625.
2009
Comparison of molecular and histological changes in zebrafish gills exposed to metallic nanoparticles.
Toxicological sciences : an official journal of the Society of Toxicology. 107(2):404-15 [DOI] 10.1093/toxsci/kfn256. [PMID] 19073994.
2009
Developing Exposure Indicators and predictive models of effects based on mechanism of action
. (92):168-178
2009
Development of a Liver Cell Line From Fathead Minnow, Pimephales Promelas, and Their Molecular and Biochemical Characterization.
In Vitro Cellular & Developmental Biology-Animal. 45:S48-S49
2009
Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.
Aquatic toxicology (Amsterdam, Netherlands). 92(3):168-78 [DOI] 10.1016/j.aquatox.2009.01.013. [PMID] 19261338.
2009
Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary.
Environmental science & technology. 43(7):2614-9 [PMID] 19452925.
2009
Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen.
BMC genomics. 10 [DOI] 10.1186/1471-2164-10-308. [PMID] 19594897.
2009
Gene expression signatures for 17α-ethinylestradiol and ZM 189,154, singly and combined, in fathead minnow testis
Bmc Genomics. (10)
2009
Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas).
Journal of proteome research. 8(5):2186-200 [DOI] 10.1021/pr800627n. [PMID] 19267455.
2009
Seasonal relationship between gonadotropin, growth hormone, and estrogen receptor mRNA expression in the pituitary gland of largemouth bass.
General and comparative endocrinology. 163(3):306-17 [DOI] 10.1016/j.ygcen.2009.04.028. [PMID] 19416730.
2009
Sequencing Research Group 2008 Study: investigation into homopolymeric amino acid N-terminal sequence tags and their effects on automated Edman degradation
. (20(4)):216-225
2009
Site-specific impacts on gene expression and behavior in fathead minnows (Pimephales promelas) exposed in situ to streams adjacent to sewage treatment plants.
BMC bioinformatics. 10 Suppl 11(Suppl 11) [DOI] 10.1186/1471-2105-10-S11-S11. [PMID] 19811676.
2009
Sources Fate and Effects of Engineered Nanomaterials in the Aquatic Environment
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2009
Spillway-induced salmon head injury triggers the generation of brain alphaII-spectrin breakdown product biomarkers similar to mammalian traumatic brain injury.
PloS one. 4(2) [DOI] 10.1371/journal.pone.0004491. [PMID] 19214235.
2009
The ABRF Edman Sequencing Research Group 2008 Study: investigation into homopolymeric amino acid N-terminal sequence tags and their effects on automated Edman degradation.
Journal of biomolecular techniques : JBT. 20(4):216-25 [PMID] 19721823.
2009
Towards functional genomics in fish using quantitative proteomics.
General and comparative endocrinology. 164(2-3):135-41 [DOI] 10.1016/j.ygcen.2009.01.023. [PMID] 19523377.
2008
Altered gene expression in the brain and liver of female fathead minnows Pimephales promelas Rafinesque exposed to fadrozole
Journal of Fish Biology. (72):2281-2340
2008
Analysis of the Transcriptomic Response To West Nile Virus Infection in the Equine Host
The American Journal of Tropical Medicine and Hygiene. 79
2008
Changes in mitochondrial gene and protein expression in grass shrimp, Palaemonetes pugio, exposed to chronic hypoxia.
Marine environmental research. 66(1):143-5 [DOI] 10.1016/j.marenvres.2008.02.046. [PMID] 18378300.
2008
Chemical contaminants, health indicators, and reproductive biomarker responses in fish from rivers in the Southeastern United States.
The Science of the total environment. 390(2-3):538-57 [PMID] 18036634.
2008
Construction of a robust microarray from a non-model species (largemouth bass) using pyrosequencing technology
Journal of Fish Biology. (72):2354-2376
2008
Construction of a robust microarray from a non-model species (largemouth bass) using pyrosequencing technology.
Journal of fish biology. 72(9):2354-2376 [PMID] 19936325.
2008
Differential Binding of Serum Proteins To Nanoparticles
International Journal of Nanotechnology. 5(1):92-115 [DOI] 10.1504/IJNT.2008.016550.
2008
Differential Binding of Serum Proteins To Nanoparticles
International Journal of Nanotechnology. 5:92-115 [DOI] 10.1504/IJNT.2008.016550.
2008
Differential binding of serum proteins to nanoparticles. International Journal of Nanotechnology
International Journal of Nanotechnology. (5):92-115
2008
Effects of cyclic hypoxia on gene expression and reproduction in a grass shrimp, Palaemonetes pugio.
The Biological bulletin. 214(1):6-16 [PMID] 18258771.
2008
Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass
. (86):459-469
2008
Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass (Micropterus salmoides).
Aquatic toxicology (Amsterdam, Netherlands). 86(4):459-69 [DOI] 10.1016/j.aquatox.2007.12.008. [PMID] 18279978.
2008
Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota.
Marine environmental research. 66(1):134-6 [DOI] 10.1016/j.marenvres.2008.02.073. [PMID] 18417205.
2008
Identification and Verification of Key Transcriptional Elements Involved in Dibutyryr Cyclic Adenosine Monophosphate (Dbcamp)-Induced Activation of the Steroidogenic Acute Regulatory Protein (Star) Gene Promoter in Largemouth Bass
Marine Environmental Research. 66
2008
Multiple Stressors Resulting in Reproductive Failure of Queen Conch (Strombus Gigas) in the Florida Keys
Marine Environmental Research. 66:52-53
2008
Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole.
Marine environmental research. 66(1):113-5 [DOI] 10.1016/j.marenvres.2008.02.072. [PMID] 18423573.
2008
Proteolysis of multiple myelin basic protein isoforms after neurotrauma: characterization by mass spectrometry
Journal of Neurochemistry. (104):1404-1414
2008
Proteolysis of multiple myelin basic protein isoforms after neurotrauma: characterization by mass spectrometry.
Journal of neurochemistry. 104(5):1404-14 [PMID] 18036155.
2008
Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells.
The Journal of steroid biochemistry and molecular biology. 108(1-2):55-63 [PMID] 17949972.
2008
Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-α and beta-β by methoxychlor and its mono-and bis-demethylated metabolites in HepG2 cells
The Journal of steroid biochemistry and molecular biology. (108):55-63
2008
Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-α and beta-β by methoxychlor and its mono-and bis-demethylated metabolites in HepG2 cells
. (108):55-63
2008
Use of cDNA macroarrays and gene profiling for detection of effects of environmental toxicants.
Methods in molecular biology (Clifton, N.J.). 410:43-53 [PMID] 18642594.
2007
A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis.
Environmental science & technology. 41(1):321-30 [PMID] 17265966.
2007
ABRF ESRG 2006 study: Edman sequencing as a method for polypeptide quantitation.
Journal of biomolecular techniques : JBT. 18(5):306-20 [PMID] 18166674.
2007
Biomarkers of contaminant exposure in Northern Pike (Esox lucius) from the Yukon River Basin, Alaska.
Archives of environmental contamination and toxicology. 52(4):549-62 [PMID] 17396212.
2007
Chemical contaminants, health indicators, and reproductive biomarker responses in fish from the Colorado River and its tributaries.
The Science of the total environment. 378(3):376-402 [PMID] 17418376.
2007
Development and validation of a 2,000-gene microarray for the fathead minnow (Pimephales promelas).
Environmental toxicology and chemistry. 26(7):1497-506 [PMID] 17665692.
2007
Distinct expression and activity profiles of largemouth bass (Micropterus salmoides) estrogen receptors in response to estradiol and nonylphenol.
Journal of molecular endocrinology. 39(4):223-37 [PMID] 17909263.
2007
Exposure to copper nanoparticles causes gill injury and acute lethality in zebrafish (Danio rerio).
Environmental science & technology. 41(23):8178-86 [PMID] 18186356.
2007
Exposure to p,p’-DDE or dieldrin during the reproductive season alters hepatic CYP expression in largemouth bass (Micropterus salmoides).
Aquatic toxicology (Amsterdam, Netherlands). 81(1):27-35 [PMID] 17145087.
2007
Exposure to p,p’-DDE or dieldrin during the reproductive season alters hepatic CYP expression in largemouth bass Micropterus salmoides
. (81):27-35
2007
Fish ‘n’ chips: the use of microarrays for aquatic toxicology.
Molecular bioSystems. 3(3):172-7 [PMID] 17308663.
2007
Integration of isoelectric focusing with multi-channel gel electrophoresis by using microfluidic pseudo-valves.
Lab on a chip. 7(12):1806-12 [PMID] 18030404.
2007
Molecular and whole animal responses of grass shrimp, Palaemonetes pugio, exposed to chronic hypoxia
Journal of Experimental Marine Biology and Ecology. (342):16-31
2007
Reproductive seasonality of the female Florida gar, Lepisosteus platyrhincus.
General and comparative endocrinology. 151(3):318-24 [PMID] 17362949.
2007
Transcriptomics and proteomics. Applications to ecotoxicology.
Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2(3):245-9 [DOI] 10.1016/j.cbd.2007.04.007. [PMID] 20483298.
2006
ABRF ESRG 2005 study: identification of seven modified amino acids by Edman sequencing.
Journal of biomolecular techniques : JBT. 17(5):308-26 [PMID] 17122064.
2006
Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin
. (78):202-206
2006
Development and validation of a direct homologous quantitative sandwich ELISA for fathead minnow (Pimephales promelas) vitellogenin.
Aquatic toxicology (Amsterdam, Netherlands). 78(2):202-6 [PMID] 16644026.
2006
Dietary exposure of largemouth bass to OCPs changes expression of genes important for reproduction
. (78):358-369
2006
Dietary exposure of largemouth bass to OCPs changes expression of genes important for reproduction.
Aquatic toxicology (Amsterdam, Netherlands). 78(4):358-69 [PMID] 16765462.
2006
Environmental contaminants and biomarker responses in fish from the Columbia River and its tributaries: spatial and temporal trends.
The Science of the total environment. 366(2-3):549-78 [PMID] 16406490.
2006
Modeling of gene expression pattern alteration by p,p’-DDE and dieldrin in largemouth bass.
Marine environmental research. 62 Suppl(Suppl):S415-9 [PMID] 16707152.
2006
Neuroproteomics in neurotrauma.
Mass spectrometry reviews. 25(3):380-408 [PMID] 16498609.
2006
Novel differential neuroproteomics analysis of traumatic brain injury in rats.
Molecular & cellular proteomics : MCP. 5(10):1887-98 [PMID] 16801361.
2006
Polychlorinated biphenyls, mercury, and potential endocrine disruption in fish from the Hudson River, New York
Aquatic Sciences. (68):206-228
2006
Temporal gene induction patterns in sheepshead minnows exposed to 17beta-estradiol.
Journal of experimental zoology. Part A, Comparative experimental biology. 305(9):707-19 [PMID] 16902967.
2006
Toxicogenomics in regulatory ecotoxicology.
Environmental science & technology. 40(13):4055-65 [PMID] 16856717.
2005
A multidimensional differential proteomic platform using dual-phase ion-exchange chromatography-polyacrylamide gel electrophoresis/reversed-phase liquid chromatography tandem mass spectrometry.
Analytical chemistry. 77(15):4836-45 [PMID] 16053296.
2005
A quantitative degradomics approach to biomarker validation by nano-LC MSMS
Analytical chemistry. (77):4836-4845
2005
Chemical cleavage of proteins in solution.
Current protocols in protein science. Chapter 11:11.4.1-11.4.11 [DOI] 10.1002/0471140864.ps1104s40. [PMID] 18429274.
2005
Derivation of major yolk proteins from parental vitellogenins and alternative processing during oocyte maturation in Fundulus heteroclitus.
Biology of reproduction. 73(4):815-24 [PMID] 15930322.
2005
Detailed endocrine assessments of wild fish in the Northern River Basins, Alberta, in comparison to EEM monitored endpoints
Water Quality Research Journal of Canada. (40 (3)):299-314
2005
Enhancement of phosphoprotein analysis using a fluorescent affinity tag and mass spectrometry.
Rapid communications in mass spectrometry : RCM. 19(15):2157-62 [PMID] 15988732.
2005
Environmental contaminants and biomarker responses in fish from the Rio Grande and its U.S. tributaries: spatial and temporal trends.
The Science of the total environment. 350(1-3):161-93 [PMID] 16227080.
2005
Molecular Indicators of Hypoxia in the Blue Crab Callinectes sapidus
Marine Ecology Progress Series. 286(286):203-215 [DOI] 10.3354/meps286203.
2005
Rapid discovery of putative protein biomarkers of traumatic brain injury by SDS-PAGE-capillary liquid chromatography-tandem mass spectrometry.
Journal of neurotrauma. 22(6):629-44 [PMID] 15941373.
2004
Differential expression of largemouth bass (Micropterus salmoides) estrogen receptor isotypes alpha, beta, and gamma by estradiol.
Molecular and cellular endocrinology. 218(1-2):107-18 [PMID] 15130515.
2004
Effects of hypoxia on gene and protein expression in the blue crab, Callinectes sapidus.
Marine environmental research. 58(2-5):787-92 [PMID] 15178114.
2004
Gene expression fingerprints of largemouth bass (Micropterus salmoides) exposed to pulp and paper mill effluents
Mutation Research. (552):19-34
2004
Gene expression fingerprints of largemouth bass (Micropterus salmoides) exposed to pulp and paper mill effluents.
Mutation research. 552(1-2):19-34 [PMID] 15288539.
2004
Induction of zona radiata and vitellogenin genes in estradiol and nonylphenol exposed male sheepshead minnows (Cyprinodon variegatus).
Marine environmental research. 58(2-5):547-51 [PMID] 15178080.
2004
Proteomics studies of traumatic brain injury.
International review of neurobiology. 61:215-40 [PMID] 15482817.
2004
Temporal and spatial variability in the estrogenicity of a municipal wastewater effluent.
Ecotoxicology and environmental safety. 57(3):303-10 [PMID] 15041253.
2004
Use of suppressive subtractive hybridization and cDNA arrays to discover patterns of altered gene expression in the liver of dihydrotestosterone and 11-ketotestosterone exposed adult male largemouth bass (Micropterus salmoides).
Marine environmental research. 58(2-5):565-9 [PMID] 15178083.
2003
ABRF-ESRG’03: analysis of a PVDF-bound known protein with a homogeneous amino-terminus.
Journal of biomolecular techniques : JBT. 14(4):278-88 [PMID] 14715886.
2003
Analysis of gene expression profiles in largemouth bass exposed to 17-beta-estradiol and to anthropogenic contaminants that behave as estrogens.
Ecotoxicology (London, England). 12(6):463-8 [PMID] 14680325.
2003
Application of proteomics technology to the field of neurotrauma.
Journal of neurotrauma. 20(5):401-7 [PMID] 12803973.
2003
Biochemical and toxicopathic biomarkers assessed in smallmouth bass recovered from a polychlorinated biphenyl-contaminated river.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 8(5):371-93 [PMID] 14602522.
2003
Differential gene expression analysis in fish exposed to endocrine disrupting compounds.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 136(2):149-61 [PMID] 14529741.
2003
Effects of pulp and paper mill effluents on reproductive success of largemouth bass.
Environmental toxicology and chemistry. 22(1):205-13 [PMID] 12503766.
2003
Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray.
EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences. 111(1T):29-36 [PMID] 12735107.
2003
Relationship between reproductive success and male plasma vitellogenin concentrations in cunner, Tautogolabrus adspersus.
Environmental health perspectives. 111(1):93-100 [PMID] 12515685.
2002
A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro.
Aquatic toxicology (Amsterdam, Netherlands). 60(1-2):101-10 [PMID] 12204590.
2002
An evaluation of biomarkers of reproductive function and potential contaminant effects in Florida largemouth bass ( Micropterus salmoidesfloridanus) sampled from the St. Johns River.
The Science of the total environment. 289(1-3):133-44 [PMID] 12049390.
2002
Array technology as a tool to monitor exposure of fish to xenoestrogens.
Marine environmental research. 54(3-5):395-9 [PMID] 12408593.
2002
Estradiol-induced gene expression in largemouth bass (Micropterus salmoides).
Molecular and cellular endocrinology. 196(1-2):67-77 [PMID] 12385826.
2002
Gene expression analysis of largemouth bass exposed to estradiol, nonylphenol, and p,p’-DDE.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 133(4):543-57 [PMID] 12470818.
2002
Vitellogenin mRNA regulation and plasma clearance in male sheepshead minnows, (Cyprinodon variegatus) after cessation of exposure to 17 beta-estradiol and p-nonylphenol.
Aquatic toxicology (Amsterdam, Netherlands). 58(1-2):99-112 [PMID] 12062157.
2002
Vitellogenin-derived yolk proteins of white perch, Morone americana: purification, characterization, and vitellogenin-receptor binding.
Biology of reproduction. 67(2):655-67 [PMID] 12135911.
2001
Altered serum sex steroids and vitellogenin induction in walleye (Stizostedion vitreum) collected near a metropolitan sewage treatment plant.
Archives of environmental contamination and toxicology. 40(3):392-8 [PMID] 11443371.
2001
Assessment of reproductive effects in largemouth bass (Micropterus salmoides) exposed to bleached/unbleached kraft mill effluents.
Archives of environmental contamination and toxicology. 41(4):475-82 [PMID] 11598785.
2001
Assessment of the estrogenicity and toxicity of a domestic wastewater effluent flowing through a constructed wetland system using biomarkers in male fathead minnows (Pimephales promelas rafinesque, 1820).
Environmental toxicology and chemistry. 20(10):2268-75 [PMID] 11596760.
2001
Chemical cleavage of proteins on membranes.
Current protocols in protein science. Chapter 11 [DOI] 10.1002/0471140864.ps1105s19. [PMID] 18429104.
2001
Determining the identity and purity of recombinant proteins by UV absorption spectroscopy.
Current protocols in protein science. Chapter 7 [DOI] 10.1002/0471140864.ps0702s01. [PMID] 18429197.
2001
Determining the identity and structure of recombinant proteins.
Current protocols in protein science. Chapter 7 [DOI] 10.1002/0471140864.ps0703s03. [PMID] 18429198.
2001
Effects of p-nonylphenol, methoxychlor, and endosulfan on vitellogenin induction and expression in sheepshead minnow (Cyprinodon variegatus).
Environmental toxicology and chemistry. 20(2):336-43 [PMID] 11351433.
2001
Identification of lysine decarboxylase as a mammalian cell growth inhibitor in Eikenella corrodens: possible role in periodontal disease.
Microbial pathogenesis. 30(4):179-92 [PMID] 11312612.
2001
Induction of gene expression in sheepshead minnows (Cyprinodon variegatus) treated with 17beta-estradiol, diethylstilbestrol, or ethinylestradiol: the use of mRNA fingerprints as an indicator of gene regulation.
General and comparative endocrinology. 121(3):250-60 [PMID] 11254367.
2001
Multiple responses in gene expression in fish treated with estrogen.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 129(2-3):277-82 [PMID] 11399460.
2001
Overview of the characterization of recombinant proteins.
Current protocols in protein science. Chapter 7 [DOI] 10.1002/0471140864.ps0701s00. [PMID] 18429195.
2001
Soluble scute proteins of healthy and ill desert tortoises (Gopherus agassizii).
American journal of veterinary research. 62(1):104-10 [PMID] 11197546.
2001
Vitellogenin-induced pathology in male summer flounder (Paralichthys dentatus).
Aquatic toxicology (Amsterdam, Netherlands). 51(4):431-41 [PMID] 11090901.
2000
Biotechnology core laboratories: An overview.
Journal of biomolecular techniques : JBT. 11(1):1-11 [PMID] 19499032.
2000
Contrasting effects of estrogen on transthyretin and vitellogenin expression in males of the marine fish, Sparus aurata.
Molecular and cellular endocrinology. 167(1-2):33-41 [PMID] 11000518.
2000
Epstein-Barr virus nuclear antigen-1 (EBNA-1) associated oligoclonal bands in patients with multiple sclerosis.
Journal of the neurological sciences. 173(1):32-9 [PMID] 10675577.
2000
Estrogen-induced vitellogenin mRNA and protein in sheepshead minnow (Cyprinodon variegatus).
General and comparative endocrinology. 120(3):300-13 [PMID] 11121295.
2000
Purification of proteins using UltraMacro spin columns or ProSorb sample preparation cartridges for amino acid analysis.
Methods in molecular biology (Clifton, N.J.). 159:31-7 [PMID] 11050714.
1999
A comparison of the reproductive physiology of largemouth bass, Micropterus salmoides, collected from the Escambia and Blackwater Rivers in Florida.
Environmental health perspectives. 107(3):199-204 [PMID] 10064549.
1999
Fathead minnow (Pimephales promelas) vitellogenin: purification, characterization and quantitative immunoassay for the detection of estrogenic compounds.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. 123(2):113-25 [PMID] 10442820.
1999
Identification of proteins electroblotted to polyvinylidene difluoride membrane by combined amino acid analysis and bioinformatics: An ABRF multicenter study.
Journal of biomolecular techniques : JBT. 10(3):129-36 [PMID] 19499016.
1999
Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences.
The Journal of biological chemistry. 274(51):36043-51 [PMID] 10593885.
1999
Serum vitellogenin levels and reproductive impairment of male Japanese Medaka (Oryzias latipes) exposed to 4-tert-octylphenol.
Environmental health perspectives. 107(5):385-90 [PMID] 10210694.
1998
Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25.
Genomics. 50(1):114-6 [PMID] 9628831.
1998
Molecular approach to find target(s) for oligoclonal bands in multiple sclerosis.
Journal of neurology, neurosurgery, and psychiatry. 65(1):48-55 [PMID] 9667560.
1996
13Bovine mitochondrial ribosomes.
Methods in enzymology. 264:237-48 [PMID] 8965698.
1996
Aminopeptidase P is disposed on human endothelial cells.
Immunopharmacology. 32(1-3):149-52 [PMID] 8796294.
1996
Modulation of rabbit reticulocyte guanine nucleotide exchange factor activity by casein kinases 1 and 2 and glycogen synthase kinase 3.
Biochemistry. 35(10):3206-12 [PMID] 8605155.
1996
The interaction of rabbit reticulocyte guanine nucleotide exchange factor eIF-2B with chain initiation factor 2: studies with N-ethylmaleimide and trypsin.
Biochemical and biophysical research communications. 223(3):604-11 [PMID] 8687443.
1996
Vitellogenin induction and reduced serum testosterone concentrations in feral male carp (Cyprinus carpio) captured near a major metropolitan sewage treatment plant.
Environmental health perspectives. 104(10):1096-101 [PMID] 8930552.
1995
A comparative study on amino acid sequences of three major isoforms of human pepsin A.
Advances in experimental medicine and biology. 362:77-81 [PMID] 8540383.
1995
Universal assay of vitellogenin as a biomarker for environmental estrogens.
Environmental health perspectives. 103 Suppl 7(Suppl 7):9-15 [PMID] 8593883.
1994
Guinea pig membrane-bound aminopeptidase P is a member of the proline peptidase family.
Biochemical and biophysical research communications. 205(3):1790-5 [PMID] 7811266.
1994
Hypoxia induces the synthesis of tropomyosin in cultured porcine pulmonary artery endothelial cells.
The American journal of physiology. 267(3 Pt 1):L271-81 [PMID] 7943254.
1994
Immunoaffinity purifications of aminopeptidase P from guinea pig lungs, kidney and serum.
Biochemical and biophysical research communications. 205(3):1796-802 [PMID] 7811267.
1994
Phosphorylation of rabbit reticulocyte guanine nucleotide exchange factor in vivo. Identification of putative casein kinase II phosphorylation sites.
Biochemistry. 33(11):3350-7 [PMID] 8136372.
1993
Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (p67).
The Journal of biological chemistry. 268(15):10796-801 [PMID] 8496145.
1992
Association of 70-kilodalton heat-shock cognate proteins with acclimation to cold.
Plant physiology. 99(4):1362-9 [PMID] 16669045.
1991
Bovine mitochondrial ribosomes possess a high affinity binding site for guanine nucleotides.
The Journal of biological chemistry. 266(15):9586-90 [PMID] 2033053.
1991
Proteins of mammalian mitochondrial ribosomes.
Biochimie. 73(6):827-35 [PMID] 1764527.
1990
The translation system of mammalian mitochondria.
Biochimica et biophysica acta. 1050(1-3):174-8 [PMID] 2169892.
1989
Mechanism of mRNA binding to bovine mitochondrial ribosomes.
The Journal of biological chemistry. 264(14):8328-38 [PMID] 2542274.
1988
Interaction of bovine mitochondrial ribosomes with Escherichia coli initiation factor 3 (IF3).
Biochemistry. 27(9):3521-7 [PMID] 3291951.
1988
RNA binding proteins of the large subunit of bovine mitochondrial ribosomes.
Nucleic acids research. 16(6):2565-83 [PMID] 3129699.
1984
Organization of proteins in mammalian mitochondrial ribosomes. Accessibility to lactoperoxidase-catalyzed radioiodination.
The Journal of biological chemistry. 259(15):9867-73 [PMID] 6086656.
1982
Protein composition of the bovine mitochondrial ribosome.
The Journal of biological chemistry. 257(15):8788-94 [PMID] 7047527.
1979
Elongation factors EF-G from E. coli and mammalian mitochondria are not functionally interchangeable.
Biochemical and biophysical research communications. 90(4):1257-65 [PMID] 391227.
1979
The effect of atractyloside and carboxyatractyloside on adenine nucleotide translocation in mitochondria of Vigna sinensis (L.) Savi cv. seridĂł.
Archives of biochemistry and biophysics. 193(2):368-72 [PMID] 464602.
1978
Antibiotic susceptibility of the peptidyl transferase locus of bovine mitochondrial ribosomes.
European journal of biochemistry. 91(2):441-8 [PMID] 365524.
1977
Atractyloside inhibition of adenine nucleotide translocation in mitochondria from hypocotyls of Vigna sinensis, (L) Savi cv. serido
Physiologia Plantarum. (41):193-196
1974
Susceptibility of 55S mitochondrial ribosomes to antibiotics inhibitory to prokaryotic ribosomes, lincomycin, chloramphenicol and PA114A.
Biochemical and biophysical research communications. 57(1):9-16 [PMID] 4597411.

Grants

Feb 2024 ACTIVE
Fate, trophic uptake, and toxicity of Per- and Polyfluoroalkyl Substance (PFAS) Mixtures in a Florida Estuary
Role: Co-Project Director/Principal Investigator
Funding: US DEPT OF INTERIOR US GEOLOGICAL SURVEY
Sep 2022 ACTIVE
Southeastern Coastal Center for Agricultural Health & Safety (SCCAHS)
Role: Project Manager
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Oct 2021 ACTIVE
INVASOMICS: Adaptive plasticity as a key for invasion success in disturbed ecosystems
Role: Principal Investigator
Funding: GOETHE UNIVERSITY via EUROPEAN COMMISSION
Sep 2020 – Aug 2022
Early-Career Gulf Research Institution Fellowship Grant Agreement
Role: Other
Funding: NATL ACADEMIES OF SCIENCE ENG AND MED
Apr 2020 ACTIVE
National Drug Early Warning System Coordinating Center
Role: Project Manager
Funding: NATL INST OF HLTH NIDA
Jan 2020 – Aug 2020
The provision of research and evaluation to determine the short and long-term human health impacts from harmful algal blooms (HABs)
Role: Co-Investigator
Funding: FL DEPT OF HLTH
Oct 2019 – Sep 2022
Unraveling the biological impacts of complex chemical mixtures and chemicals of emerging concern
Role: Principal Investigator
Funding: US ARMY ENG RES AND DEVELOPMENT CENTER
Dec 2018 – Mar 2020
Persistent occurrence of glyphosate in the Lake Okechobee area and effects on the immune system of manatees
Role: Other
Funding: EVERGLADES FOUNDATION
Aug 2018 – Aug 2023
Drinking Water Treatment Residuals as Material for in situ Capping of Metal-Contaminated Sediments
Role: Co-Project Director/Principal Investigator
Funding: SERDP-STRATEGIC ENV R AND D PROG via US DEPT OF DEFENSE
Jan 2018 – Jun 2020
Designing Nanoparticle-based Dispersants with Improved Efficiency and Biocompatibility
Role: Co-Investigator
Funding: GULF OF MEXICO RESEARCH INITIATIVE via BP EXPLORATION & PRODUCTION
Aug 2017 – Jan 2019
Ex Vivo Verification of Hard and Soft Acid-Base (HSAB) Rank Predictions for Protein Adducts & Histopathology
Role: Co-Investigator
Funding: US ENVIRONMENTAL PRO AGCY
Apr 2017 – Feb 2018
Early Life Effects of Produced Water on Menidia Beryllina
Role: Principal Investigator
Funding: ENVIRONMENTAL DEFENSE
Sep 2016 – Sep 2018
Toxicity Screen for Eastern Mosquitofish Exposed to the Ultraviolet Screen Chemical Benzophenone-3
Role: Principal Investigator
Funding: US DEPT OF INTERIOR US GEOLOGICAL SURVEY
Jan 2016 – Jun 2016
ENZYMATIC TESTING OF RESTORSEA CR?MES — PROJECT 10
Role: Principal Investigator
Funding: BIOREGENCY
Oct 2015 – Feb 2018
DEVELOPMENT OF A HTS ASSAY FOR A NEUROLOGICAL LYSOSOMALDISEASE
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Oct 2015 – Dec 2015
ENZYMATIC TEST OF RESTORSEA DAY CREAM SAMPLES
Role: Principal Investigator
Funding: BIOREGENCY
Jul 2015 – Aug 2015
Enzymatic testing of egg-hatching fluid-part 6
Role: Principal Investigator
Funding: BIOREGENCY
May 2015 – May 2018
Evaluating Emerging Contaminants of Concern in Waterbodies
Role: Principal Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT
Mar 2015 – Feb 2016
Applied Biosystems SCIEX Q-TRAP 6500 LC/MS/MS Mass Spectrometer
Role: Principal Investigator
Funding: NATL INST OF HLTH OD
Mar 2015 – Feb 2016
DRS MATCH: APPLIED BIOSYSTEMS SCIEX Q-TRAP 6500 LC/MS/MSMASS SPECTROMETER
Role: Principal Investigator
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Jul 2014 – Jun 2016
DISSERTATION RESEARCH: Behavioral and Reproductive Implications of Nanomaterial and Synthetic Estrogen Co-Exposures in Fish
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Jul 2014 – Jul 2015
Protein Profiling of Aquabeautine XL (fish hatching fluid)
Role: Principal Investigator
Funding: BIOREGENCY
Jul 2014 – Jun 2018
BIOANALYTICAL TOOLS: Linkage of In Vitro Assay Results With In Vivo End Points
Role: Principal Investigator
Funding: San Francisco Estuary Institute
Sep 2012 – Aug 2016
Impact of Single-Walled Carbon Nanotubes on Growth and Reproductive Parameters in Fish
Role: Project Manager
Funding: NATL SCIENCE FOU
Sep 2011 – Jun 2016
In Situ sampling tool and approach for assessing bioavailability and toxicity of sediment contaminants.
Role: Principal Investigator
Funding: ARIZONA STATE UNIVERSITY via NATL INST OF HLTH
Sep 2004 – Jun 2017
Environmental Estrogens
Role: Principal Investigator
Funding: UF RESEARCH FOU SALARY EXPENSE TRANSFERS

Education

PhD Biochemistry and Molecular Biology
1975 · University of Florida
MS Biochemistry and Molecular Biology
1967 · Yale University
BS Chemistry
1966 · Mary Washington College

Contact Details

Phones:
Business:
(352) 294-4642
Emails:
Business:
ndenslow@ufl.edu
Addresses:
Business Mailing:
PO Box 110885
DR NANCY DENSLOW
GAINESVILLE FL 32611
Business Street:
RM 6 BUILDING 471, MOWRY RD
DR. NANCY DENSLOW
GAINESVILLE FL 32611