The Analytical Toxicology Core Laboratory (ATCL) at the University of Florida provides
comprehensive analytical support to on-campus and off-campus researchers requiring
qualitative and/or quantitative chemical analysis to meet study objectives. Equipped with
state-of- the-art instrumentation and staffed with personnel experienced in handling
complex biological tissues, the ATCL is a resource for method development, as well as
for routine analyses that include a wide range of chemicals.
The ATCL serves a broad array of clients, including UF investigators from the colleges of
Medicine, Nursing, Pharmacy, Veterinary Medicine, Engineering, Liberal Arts and
Sciences, and the Institute of Food & Agricultural Sciences (IFAS). Off campus clients
have included investigators at other universities, law enforcement and legal firms, and
public and private companies, including both large and small pharmaceutical companies.
Despite the laboratory name, the focus is not exclusively on toxic substances, and the
laboratory supports a wide range of biomedical and nutritional research. In addition to
analytical support for preclinical and clinical trials, the ATCL has also handled numerous
analytes in human and animal studies for a variety of drugs, environmental
contaminants, and endogenous biochemical species, along with their respective
metabolites. In addition to research support, the ATCL has conducted stability studies
and provided external validation for pharmaceutical preparations and acted as a
resource for drug diversion and/or abuse testing. On request, the ATCL has also
provided analytical assistance to law enforcement for criminal investigations. The
laboratory has recently expanded its capabilities to include lipidomics and non-targeted
Located within the Center for Environmental and Human Toxicology, under the
technical direction of Dr. Viet Dang and Dr. Matthew Booth, the ATCL is a non-profit
service activity of the University of Florida.