Stephen M Roberts, PhD
Professor; Program Director
Department:
Department of Physiological Sciences
Business Phone:
(352) 294-4514
Business Email:
smroberts@ufl.edu
Accomplishments
UF Term Professorship
2017
·
University of Florida
Technical Committee on Food and Chemical Safety
2014-2020
·
ILSI North America
Chemical Assessment Advisory Committee
2012-2018
·
U.S. EPA
Science Advisory Board (Chartered)
2006-2013
·
U.S. EPA
Science Advisory Board
2006-2010
·
National Center for Toxicological Research, U.S. FDA
Board of Scientific Counselors
2002-2005
·
National Toxicology Program, DHHS
UF Research Foundation Professorship
2001
·
University of Florida
FIFRA Scientific Advisory Panel
1999-2005
·
U.S. EPA
Pfizer Award for Research Excellence
1998
·
Pfizer
Teaching Profile
Courses Taught
2020-2023
PAS5026 Pharmacotherapeu 2
2008-2010,2015-2022
VME6602 General Toxicology
2008,2015-2022
VME6605 Toxic Substances
2006,2009-2018
VME6607 Human Health Risk Assessment
2018
VME7980 Research for Doctoral Dissertation
2016
VME6932 Seminar in Physiological Sciences
2010,2012-2015,2015
PHC6601 Seminar in Contemporary Public Health Issues
2011-2013,2015
PHC6946 Public Health Internship
2013-2014,2023-2025
BMS6031 Foundations of Med
2006-2009,2011
VME4906 Problems in Veterinary Science
2006
VME6934 Topics in Veterinary Medical Sciences
Research Profile
Mechanisms of drug and chemical toxicity; Cell defense mechanisms against toxicity; Toxicokinetics, particularly bioavailability of environmental contaminants; Risk assessment; Nanomaterial toxicity
Publications
Academic Articles
2024
A simulation study of extrapolation uncertainty in exposure assessment – Use of pilot study results for site investigation.
Journal of environmental management.
356
[DOI] 10.1016/j.jenvman.2024.120692.
[PMID] 38547828.
2023
High-precision Pb isotopes of drinking water lead pipes: Implications for human exposure to industrial Pb in the United States.
The Science of the total environment.
871
[DOI] 10.1016/j.scitotenv.2023.162067.
[PMID] 36758690.
2023
The use of serum protein analysis in the diagnosis of fatal envenomation via Crotalus horridus (timber rattlesnake).
Journal of forensic sciences.
68(2):711-715
[DOI] 10.1111/1556-4029.15213.
[PMID] 36715131.
2022
Assessment of the bioaccessibility of glyphosate in soil using a physiologically based extraction test
Human and Ecological Risk Assessment: An International Journal.
28(3-4):316-325
[DOI] 10.1080/10807039.2022.2049440.
2022
Effect of soil particle size and extraction method on the oral bioaccessibility of arsenic
Journal of Toxicology and Environmental Health, Part A.
85(13):538-552
[DOI] 10.1080/15287394.2022.2048935.
2022
Plasma l‐indospicine and 3‐nitropropionic acid in ponies fed creeping indigo: Comparison with results from an episode of presumptive creeping indigo toxicosis
Equine Veterinary Journal.
54(1):145-152
[DOI] 10.1111/evj.13415.
2022
Review of regulatory reference values and background levels for heavy metals in the human diet
Regulatory Toxicology and Pharmacology.
130
[DOI] 10.1016/j.yrtph.2022.105122.
2021
Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research.
Environmental toxicology and chemistry.
40(3):606-630
[DOI] 10.1002/etc.4890.
[PMID] 33017053.
2020
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clams.
Regulatory toxicology and pharmacology : RTP.
117
[DOI] 10.1016/j.yrtph.2020.104759.
[PMID] 32768666.
2020
Probabilistic risk assessment for high-end consumers of seafood on the northeastern Gulf coast.
Journal of exposure science & environmental epidemiology.
30(3):478-491
[DOI] 10.1038/s41370-019-0119-4.
[PMID] 30728481.
2019
Bioaccessibility of polychlorinated dioxins and furans in soil from a Superfund site
Chemosphere.
214:418-423
[DOI] 10.1016/j.chemosphere.2018.09.044.
2019
Derivation of a chronic reference dose for perfluorohexane sulfonate (PFHxS) for reproductive toxicity in mice
Regulatory Toxicology and Pharmacology.
108
[DOI] 10.1016/j.yrtph.2019.104452.
2018
Incremental Sampling Methodology: Applications for Background Screening Assessments.
Risk analysis : an official publication of the Society for Risk Analysis.
38(1):194-209
[DOI] 10.1111/risa.12820.
[PMID] 28556091.
2018
Influence of airborne particulates on respiratory tract deposition of inhaled toluene and naphthalene in the rat
Inhalation Toxicology.
30(1):19-28
[DOI] 10.1080/08958378.2018.1438539.
2018
Targeted heat activation of HSP promoters in the skin of mammalian animals and humans.
Cell stress & chaperones.
23(4):455-466
[DOI] 10.1007/s12192-018-0875-4.
[PMID] 29417383.
2017
Influence of PEG coating on the oral bioavailability of gold nanoparticles in rats.
Drug delivery.
24(1):591-598
[DOI] 10.1080/10717544.2017.1282554.
[PMID] 28222611.
2017
Molecular Mechanisms of Perfluorooctanoate-Induced Hepatocyte Apoptosis in Mice Using Proteomic Techniques.
Environmental science & technology.
51(19):11380-11389
[DOI] 10.1021/acs.est.7b02690.
[PMID] 28885018.
2016
Applied Nanotoxicology.
International journal of toxicology.
35(1):5-16
[DOI] 10.1177/1091581816628484.
[PMID] 26957538.
2016
Distribution and accumulation of 10 nm silver nanoparticles in maternal tissues and visceral yolk sac of pregnant mice, and a potential effect on embryo growth.
Nanotoxicology.
10(6):654-61
[DOI] 10.3109/17435390.2015.1107143.
[PMID] 26593872.
2016
Effects of Source and Concentration on Relative Oral Bioavailability of Benzo(a)pyrene from Soil.
Environmental science & technology.
50(20):11274-11281
[PMID] 27617342.
2016
Oral Bioavailability, Bioaccessibility, and Dermal Absorption of PAHs from Soil-State of the Science.
Environmental science & technology.
50(5):2151-64
[DOI] 10.1021/acs.est.5b04110.
[PMID] 26824144.
2015
Differential interferences with clinical chemistry assays by gold nanorods, and gold and silica nanospheres.
Nanotoxicology.
9(1):116-25
[DOI] 10.3109/17435390.2014.894151.
[PMID] 24620736.
2015
Oral absorption of PEG-coated versus uncoated gold nanospheres: does agglomeration matter?
Particle and fibre toxicology.
12
[DOI] 10.1186/s12989-015-0085-5.
[PMID] 25884802.
2014
Measurement of nanomaterials in foods: integrative consideration of challenges and future prospects.
ACS nano.
8(4):3128-35
[DOI] 10.1021/nn501108g.
[PMID] 24673283.
2013
Derivation of a chronic reference concentration for decalin.
Regulatory toxicology and pharmacology : RTP.
66(1):38-46
[DOI] 10.1016/j.yrtph.2013.02.011.
[PMID] 23454102.
2012
Influence of Suwannee River humic acid on particle properties and toxicity of silver nanoparticles.
Chemosphere.
89(1):96-101
[DOI] 10.1016/j.chemosphere.2012.04.024.
[PMID] 22583785.
2012
The delivery of a health promotion intervention by a public health promotion specialist improves patient satisfaction in the emergency department.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.
19(3):313-7
[DOI] 10.1111/j.1553-2712.2012.01293.x.
[PMID] 22435864.
2010
Derived Reference Doses (RfDs) for the environmental degradates of the herbicides alachlor and acetochlor: results of an independent expert panel deliberation.
Regulatory toxicology and pharmacology : RTP.
57(2-3):220-34
[DOI] 10.1016/j.yrtph.2010.02.010.
[PMID] 20206657.
2010
Nanoparticle characterization for cancer nanotechnology and other biological applications.
Methods in molecular biology (Clifton, N.J.).
624:39-65
[DOI] 10.1007/978-1-60761-609-2_4.
[PMID] 20217588.
2009
A qualitative study of junior high school principals’ and school food service directors’ experiences with the Texas school nutrition policy.
Journal of nutrition education and behavior.
41(4):293-9
[DOI] 10.1016/j.jneb.2008.05.010.
[PMID] 19508936.
2008
Comparison of chlordecone and estradiol effects on splenic T-cells in (NZBxNZW)F(1) mice.
Toxicology letters.
183(1-3):1-9
[DOI] 10.1016/j.toxlet.2008.08.020.
[PMID] 18951962.
2008
Differential Binding of Serum Proteins To Nanoparticles
International Journal of Nanotechnology.
5(1):92-115
[DOI] 10.1504/IJNT.2008.016550.
2008
Differential binding of serum proteins to nanoparticles. International Journal of Nanotechnology
International Journal of Nanotechnology.
(5):92-115
2008
Differential binding of serum proteins to nanoparticles. International Journal of Nanotechnology
International Journal of Nanotechnology.
(5):92-115
2008
Prevention of chemotherapy-induced alopecia in rodent models.
Cell stress & chaperones.
13(1):31-8
[DOI] 10.1007/s12192-007-0005-1.
[PMID] 18347939.
2007
Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and estradiol in (NZBxNZW)F1 mice.
Toxicological sciences : an official journal of the Society of Toxicology.
99(1):141-52
[PMID] 17578864.
2007
Body weight distributions for risk assessment.
Risk analysis : an official publication of the Society for Risk Analysis.
27(1):11-26
[PMID] 17362397.
2007
Diminished prolactin from chlordecone treatment in ovariectomized (NZBxNZW)F(1) mice.
International immunopharmacology.
7(13):1808-12
[PMID] 17996692.
2007
Relative oral bioavailability of arsenic from contaminated soils measured in the cynomolgus monkey.
Toxicological sciences : an official journal of the Society of Toxicology.
95(1):281-8
[PMID] 17005634.
2006
Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice.
Toxicology.
218(2-3):81-9
[PMID] 16309813.
2006
Increased hepatotoxicity of acetaminophen in Hsp70i knockout mice.
Toxicology and applied pharmacology.
210(1-2):157-62
[PMID] 16280147.
2006
Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation.
Toxicological sciences : an official journal of the Society of Toxicology.
90(2):296-303
[PMID] 16407094.
2005
Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.
Environmental health perspectives.
113(3):323-8
[PMID] 15743722.
2005
Heat shock proteins and acquired resistance to uranium nephrotoxicity.
Toxicology.
206(1):59-73
[PMID] 15590109.
2005
Manipulating heat shock protein expression in laboratory animals.
Methods (San Diego, Calif.).
35(2):149-57
[PMID] 15649841.
2005
Novel gene switches for targeted and timed expression of proteins of interest.
Molecular therapy : the journal of the American Society of Gene Therapy.
12(2):290-8
[PMID] 15925546.
2003
Cocaine-protein targets in mouse liver.
Biochemical pharmacology.
66(1):105-13
[PMID] 12818370.
2002
Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride).
Regulatory toxicology and pharmacology : RTP.
35(1):44-55
[PMID] 11846635.
2002
Measurement of arsenic bioavailability in soil using a primate model.
Toxicological sciences : an official journal of the Society of Toxicology.
67(2):303-10
[PMID] 12011490.
Grants
Jul 2021
– Jun 2022
Toxicological Support Services 2021-2022
Role: Co-Project Director/Principal Investigator
Funding: FL DEPT OF HLTH ENVIRONMENTAL HEALTH
Nov 2020
– Nov 2021
Chemical Measures of PAH Bioavailability to Improve Human Health Risk Assessment of Contaminated Sites – In Vivo Studies for Naval Information Warfare Center (NIWC), Pacific, located in San Diego, CA
Role: Principal Investigator
Funding: US ARMY CORPS OF ENGINEERS
Jan 2020
– Aug 2020
The provision of research and evaluation to determine the short and long-term human health impacts from harmful algal blooms (HABs)
Role: Co-Investigator
Funding: FL DEPT OF HLTH
Nov 2019
– Mar 2020
Toxicological support services
Role: Co-Project Director/Principal Investigator
Funding: FL DEPT OF HLTH ENVIRONMENTAL HEALTH
Apr 2019
– Mar 2024
Development of a Community-Based Lead Risk Mitigation Model
Role: Project Manager
Funding: CORNWELL RESEARCH GROUP
via US ENVIRONMENTAL PRO AGCY
Feb 2018
– Feb 2022
Miami Dade Multi Sponsors
Role: Principal Investigator
Funding: MIAMI-DADE CNTY
Apr 2017
– Mar 2019
Rapid risk assessment of chronic domoic acid exposure in WA razor clam harvesters
Role: Co-Investigator
Funding: UNIV OF MARYLAND BALTIMORE
via NATL INST OF HLTH NIEHS
Mar 2017
– Sep 2017
Dioxin Bioaccessibility Assessment for the American Creosote Works Site Center for Environmental & Human Toxicology
Role: Principal Investigator
Funding: GEOSYNTEC
via FL DEPT OF ENVIRONMENTAL PROTECT
May 2014
– Dec 2017
Influence of Particulates on Pulmonary Deposition of VOCs
Role: Principal Investigator
Funding: ELECTRIC POWER RES INST
Oct 2012
– Jan 2018
Miami Dade Multiple Sponsors
Role: Principal Investigator
Funding: MULTIPLE SPONSORS
Jun 2011
– Apr 2017
Health Impact of Deepwater Horizon Spill in Eastern Gulf Coast Communities
Role: Project Manager
Funding: NATL INST OF HLTH NIEHS
Aug 2010
– Jun 2020
Toxicological Support Services
Role: Principal Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT
via US ENVIRONMENTAL PRO AGCY
Aug 2010
– Jun 2020
Toxicological Support Services
Role: Principal Investigator
Funding: FL DEPT OF ENVIRONMENTAL PROTECT
Apr 2007
– Sep 2024
Center of Excellence – Center for Nano-Biosensors
Role: Project Manager
Funding: STATE UNIV SYS OF FL BOARD OF GOVERNORS
Education
NIH Postdoctoral fellow
1978-1980
·
School of Pharmacy, SUNY Buffalo
Doctor of Philosophy
1977
·
College of Medicine, University of Utah
Bachelor of Science in Pharmacy
1973
·
College of Pharmacy, Oregon State University
Contact Details
Phones:
- Business:
- (352) 294-4514
Emails:
- Business:
- smroberts@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 110885
GAINESVILLE FL 32611 - Business Street:
-
2187 Mowry Rd. Univ. of Florida
GAINESVILLE FL 32611