Analytical Toxicology Core Laboratory
The Analytical Toxicology Core Laboratory at the University of Florida provides comprehensive analytical support to on-campus and off-campus researchers requiring qualitative and/or quantitative chemical analysis to meet study objectives.
The Analytical Toxicology Core Laboratory (ATCL) at the University of Florida provides comprehensive analytical support to on-campus and off-campus researchers requiring qualitative and/or quantitative chemical analysis to meet study objectives. Equipped with state-of-the-art instrumentation and staffed with personnel experienced in handling complex biological samples, the ATCL is an available resource for method development, as well as for routine analyses which include a wide range of environmental contaminants, drugs, and other toxins from a variety of environmental (soil, water, marine seiments, etc.) and biological (blood, urine, bowel contents, tissues, milk, plants, matrices, exosomes, cell culture, etc.).
With the primary mission of supporting basic and applied research, the skills, knowledge, and experience of the scientific staff is available to assist investigators in the proposal phase of new research to ensure competitive grant application. Early phase assistance frequently includes the generation of sample collection and preservation protocols, the development and/or description of methodology to meet stated objectives, customization of quality assurance protocols, and the production of preliminary data. In addition to supporting research in the fields of human, environmental and forensic toxicology, the ATCL performs analysis in support of the pharmaceutical industry and offers analytical method development, validation, and the preparation of data for IND applications and for court testimony, as required by individual projects. Located within the Center for Environmental and Human Toxicology, the ATCL is a non-profit service activity of the University of Florida.
Routine Analyses
- Organochlorine pesticide residues (up to 30 target analytes, including toxaphene and technical grade chlordane) from environmental and biological samples.
- Organophosphate pesticide residues with a catalog of ???? that are relevant for environmental (soil, water) and biological research.
- Glyphosate and 2,4-D stand alone in both environmental and biological matrices.
- Polyaromatic hydrocarbons (PAH’s), as selected analytes or total, from environmental or biological samples.
- Polychlorinated biphenyls (PCB’s), as selected congeners, total, or Arochlor from environmental or biological samples.
- Volatile and semivolatile organic compounds from environmental samples.
- Steroid hormones including E2, EE2, Testosterone, cortisol, corticosterone, among others from environmental and biological samples.
- Lipidomics analysis for biological samples.
- Fatty acid panel (over 30 target analytes) from biological tissues samples.
- Isoflavones (aglycones, conjugated, total) from cultures, biological samples or commercial products.
- Short chain fatty acids in different biological samples.
- Algal toxins and microcistines by LC-MS-MS in environmental and biological samples.
- Custom Analyses
- Development/modification of analytical methods to meet specific needs
For more information or to discuss potential analyses, please contact:
Marianne Kozuch, Ph.D
Center for Environmental & Human Toxicology
University of Florida
Box 110885
Building 471, Mowry Road
Gainesville, FL 32611
352-294-4621
FAX: 352-392-4707