Analytical

Analytical Toxicology Core Laboratory

The Analytical Toxicology Core Laboratory at the University of Florida provides comprehensive analytical support to on-campus and off-campus researchers requiring qualitative and/or quantitative chemical analysis to meet study objectives.

Doing Experiments

The Analytical Toxicology Core Laboratory (ATCL) at the University of Florida provides comprehensive analytical support to on-campus and off-campus researchers requiring qualitative and/or quantitative chemical analysis to meet study objectives. We are equipped with state-of-the-art instrumentation and staffed with personnel who are experienced in handling complex biological and environmental samples. The ATCL is an excellent resource for method development, as well as for routine analyses which include a wide range of environmental contaminants, drugs, and other toxins from a variety of environmental (soil, water, marine sediments) and biological matrices (blood, urine, bowel contents, tissues, milk, plants, exosomes, cell cultures).

With the primary mission of supporting basic and applied research, the skills, knowledge, and experience of the scientific staff is available to assist investigators in the proposal phase of new research to ensure competitive grant application. Early phase assistance frequently includes the generation of sample collection and preservation protocols, the development and/or description of methodology to meet stated objectives, customization of quality assurance protocols, and the production of preliminary data. In addition to supporting research in the fields of human, environmental and forensic toxicology, the ATCL performs analysis in support of the pharmaceutical industry and offers analytical method development, validation, and the preparation of data for investigational new drug applications and for court testimony, as required by individual projects. Located within the Center for Environmental and Human Toxicology, the ATCL is a non-profit service entity of the University of Florida.

Routine Analyses

  • Organochlorine pesticides from environmental and biological samples
  • Organophosphate pesticides that are relevant to environmental and biological research
  • Glyphosate and 2,4-D in both environmental and biological matrices
  • Polyaromatic hydrocarbons (PAH)
  • Polychlorinated biphenyls (PCB)
  • Volatile and semivolatile organic compounds
  • Steroid hormones including E2, EE2, testosterone, cortisol, corticosterone, among others
  • Lipidomics analysis
  • Fatty acids (over 30 target analytes)
  • Isoflavones (aglycones, conjugated, total) from cultures, biological samples or commercial products
  • Short chain fatty acids
  • Algal toxins and microcystins from water and biological samples
  • Custom analysis
  • Development and/or modification of analytical methods to meet specific needs

For more information or to discuss potential analyses, please contact:
Marianne Kozuch, Ph.D
Center for Environmental & Human Toxicology
University of Florida
Box 110885
Building 471, Mowry Road
Gainesville, FL 32611
352-294-4621
FAX: 352-392-4707